DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DnaJ-1 and dnajb5

DIOPT Version :9

Sequence 1:	NP_523936.2	Gene:	DnaJ-1 / 38643	FlyBaseID:	FBgn0263106	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	XP_012821923.1	Gene:	dnajb5 / 100487123	XenbaseID:	XB-GENE-995211	Length:	407	Species:	Xenopus tropicalis

Alignment Length:	352	Identity:	178/352 - (50%)
Similarity:	235/352 - (66%)	Gaps:	25/352 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKDFYKILGLERKASDDEIKKAYRKLALKYHPDKNKSPQAEERFKEIAEAYEVLSDKKKRDIFD 65
            ||||:||||||...|::|||||||||:||||||||||...||::||||||||:||||.|||.::|
Frog    60 MGKDYYKILGLASGANEDEIKKAYRKMALKYHPDKNKDANAEDKFKEIAEAYDVLSDPKKRAVYD 124

  Fly    66 NYGEDGLKGGQPGPDGGGQPGAYTYQFHGDPRATFAQFFGSSDPFGAFFTGGDNMFSGG---QGG 127
            .|||:|||.|  |...|....::.|.|||||.||||.|||.|:||..||....:..|.|   :..
Frog   125 QYGEEGLKTG--GGSTGNTGSSFHYTFHGDPHATFASFFGGSNPFDIFFGSSRSRMSNGFDHEDM 187

  Fly   128 NTNE----IFWNIGGDDMFAFNA----------QAPSRKRQQDPPIEHDLFVSLEEVDKGCIKKM 178
            :.||    :|   ||...|.|:.          |..||::.||||:.|:|.|||||:..||.|:|
Frog   188 DINEDEDDLF---GGFGRFGFSGVNGFHKRHQDQLHSRRKVQDPPVVHELKVSLEEIYHGCTKRM 249

  Fly   179 KISRMATGSNG--PYKEEKVLRITVKPGWKAGTKITFPQEGDSAPNKTPADIVFIIRDKPHSLFK 241
            ||:|.....:|  ...|:|:|.:.:|.|||.|||||||:|||:.....||||||:::||||:|||
Frog   250 KITRRRLNPDGRTVRTEDKILNVVIKKGWKEGTKITFPKEGDATSENIPADIVFLLKDKPHALFK 314

  Fly   242 REGIDLKYTAQISLKQALCGALVSVPTLQGSRIQVNPNHEIIKPTTTRRINGLGLPVPKEPSRRG 306
            |:|.::.|||:|:||:||||..|::||:.| |:...|..::|||...:|:.|.|||.||.|::||
Frog   315 RDGSNIVYTAKITLKEALCGCTVNIPTIDG-RVIPLPCSDVIKPGAVKRLRGEGLPFPKVPNQRG 378

  Fly   307 DLIVSFDIKFPDTLAPSLQNQLSELLP 333
            ||||.|.::|||.:....:..|.:.||
Frog   379 DLIVEFQVRFPDRIPQPTRELLKQHLP 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DnaJ-1	NP_523936.2	DnaJ	1..333	CDD:223560	176/350 (50%)
		DnaJ	4..65	CDD:278647	44/60 (73%)
		DnaJ_C	157..320	CDD:199909	86/164 (52%)
dnajb5	XP_012821923.1	DnaJ	60..402	CDD:223560	176/347 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53515
OrthoDB	1	1.010	-	-		D1393097at2759
OrthoFinder	1	1.000	-	-		FOG0000274
OrthoInspector	1	1.000	-	-		mtm9327
Panther	1	1.100	-	-	O	PTHR24078
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1020
SonicParanoid	1	1.000	-	-		X227
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.060