Protein Alignment Sse and ESPL1

DIOPT Version :10

• Sequence 1: NP_523935.1
• Gene: Sse / 38640
• FlyBaseID: FBgn0035627
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_036423.4
• Gene: ESPL1 / 9700
• HGNCID: 16856
• Length: 2120
• Species: Homo sapiens
• Alignment Length: 523
• Identity: 117/523 - (22%)
• Similarity: 204/523 - (39%)
• Gaps: 87/523 - (16%)

  Fly    60 LTESAELENQRPTAEELIKSATKLEKKDYKSKKFLQNIIKYLQQMEQEKQP-KKPINEIPEYLDF 123
            :|||..:..:......|.:..:|.:|     .:....|...||.:..::.| ..|:..|.....|
Human  1620 VTESVSITCRHQLLTHLHRQLSKAQK-----HRGSLEIADQLQGLSLQEMPGDVPLARIQRLFSF 1679

  Fly   124 --LDDVQDPTEGLTRISEKCNSLPQ--EWCVLQLCKSFNPATTYSVFNEIIASDGAIYLTLLRHC 184
              |:....|........|:...:|.  ..|||.|. :..|              |.:..|||...
Human  1680 RALESGHFPQPEKESFQERLALIPSGVTVCVLALA-TLQP--------------GTVGNTLLLTR 1729

  Fly   185 RSSQLGPICLKI-SNENTANLFREYSTLVERFRRVVTVDPLNMKGKE-----AKQKYWEELNGFD 243
            ......|:.::| :.:|..:|    .:::..|      |.:....||     .|:::|......|
Human  1730 LEKDSPPVSVQIPTGQNKLHL----RSVLNEF------DAIQKAQKENSSCTDKREWWTGRLALD 1784

  Fly   244 TFQQKLLADF-RDIISPYSFLFFGKRYDCTVVQKQIKATYTRVDDFCLLNQWGTHQRVLLSQAAS 307
            ...:.|:|.. :.::..:..|......:....|:.     :|:.:......|....|.||....|
Human  1785 HRMEVLIASLEKSVLGCWKGLLLPSSEEPGPAQEA-----SRLQELLQDCGWKYPDRTLLKIMLS 1844

  Fly   308 HANRLEIADLKLICYELSSNENE-----IQSAYELLKGLASDWAEVEERQPLASRRFPIILVVDE 367
            .|..|...|::.:.|.|...:.|     :..|...|:||.         .|..|.   ::||:|:
Human  1845 GAGALTPQDIQALAYGLCPTQPERAQELLNEAVGRLQGLT---------VPSNSH---LVLVLDK 1897

  Fly   368 RLDHLHWEQLVTVQEF--SRVKSLHCLWRLFQNHKSNIKHGYYTTNIKRGM------CVINPDAD 424
            .|..|.||.:.::|..  :|:.|..     |....|.||....:..:.:|:      .|:||..:
Human  1898 DLQKLPWESMPSLQALPVTRLPSFR-----FLLSYSIIKEYGASPVLSQGVDPRSTFYVLNPHNN 1957

  Fly   425 LVNSGRRLRSFFEYWLSQ--WQHLFETVPNEEVMVKQALQADCFVYAGHGSGLQYVNGRIICRAR 487
            |.::..:.|:.|.   |:  |:.:...||..|.:.:...:.|.::|||||:|.::::|:.:.|..
Human  1958 LSSTEEQFRANFS---SEAGWRGVVGEVPRPEQVQEALTKHDLYIYAGHGAGARFLDGQAVLRLS 2019

  Fly   488 VRSVVFLFGCDSTRMLGTGLYSALYGAHDY--YHGALCPSIVGTLMPALDGNMDTVSVTILSRWL 550
            .|:|..||||.|..:...|   .|.||...  |..|.||..:|.|....|.::|..:..:|..||
Human  2020 CRAVALLFGCSSAALAVRG---NLEGAGIVLKYIMAGCPLFLGNLWDVTDRDIDRYTEALLQGWL 2081

  Fly   551 APG 553
            ..|
Human  2082 GAG 2084

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sse	NP_523935.1	Peptidase_C50	171..530	CDD:460974	88/382 (23%)
ESPL1	NP_036423.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1299..1355
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1412..1485
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1507..1561
		Peptidase_C50	1721..2069	CDD:460974	89/385 (23%)