DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Blimp-1 and MIG3

DIOPT Version :9

Sequence 1:	NP_001261442.1	Gene:	Blimp-1 / 38638	FlyBaseID:	FBgn0035625	Length:	1216	Species:	Drosophila melanogaster
Sequence 2:	NP_010945.1	Gene:	MIG3 / 856750	SGDID:	S000000830	Length:	394	Species:	Saccharomyces cerevisiae

Alignment Length:	267	Identity:	67/267 - (25%)
Similarity:	103/267 - (38%)	Gaps:	50/267 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   915 ERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDI--CKKRFSSTSNLKTHLRLHS-------- 969
            :|||:|.:|::.|.:|.|.::|...|||||||:|.:  |.|.||.:..||.|||.|:
Yeast    14 QRPFRCEICSRGFHRLEHKKRHGRTHTGEKPHKCTVQGCPKSFSRSDELKRHLRTHTKGVQRRRI 78

  Fly   970 ---GQKPYACD---LCPQKFTQFVHLKLHKRLHTNDRPY---VCQGCDKKYISASGLRTHWKTTS 1025
               |.:....:   ..|..|.:...:.|.....:...|.   |.|.||...|..:|
Yeast    79 KSKGSRKTVVNTATAAPTTFNENTGVSLTGIGQSKVPPILISVAQNCDDVNIRNTG--------- 134

  Fly  1026 CKPNNLEEELAMAAAATSECLDKD-HPEPDSREAYEQLTQ--HMHPAVHPGLRHLSSGGQSPPRL 1087
             ..|.:.|..|.|.......:..| ||.|.|... ..:|.  .::|:..| .::|.||....|..
Yeast   135 -NNNGIVETQAPAILVPVINIPNDPHPIPSSLST-TSITSIASVYPSTSP-FQYLKSGFPEDPAS 196

  Fly  1088 IPL----GNHMAPQQQSHQQ---QQQQHQQQGVPPPHLLMTQHSVGPAPMLLTTASQLPPPPPHH 1145
            .|.    |:.:|..:.|...   .:.:.....:..|..|.:..:...|.:|..|:         |
Yeast   197 TPYVHSSGSSLALGELSSNSSIFSKSRRNLAAMSGPDSLSSSKNQSSASLLSQTS---------H 252

  Fly  1146 QQNSPSR 1152
            ...|.||
Yeast   253 PSKSFSR 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Blimp-1	NP_001261442.1	SET	133..260	CDD:214614
		C2H2 Zn finger	892..912	CDD:275368
		zf-H2C2_2	904..929	CDD:290200	6/13 (46%)
		C2H2 Zn finger	920..940	CDD:275368	6/19 (32%)
		zf-H2C2_2	932..957	CDD:290200	13/26 (50%)
		C2H2 Zn finger	948..968	CDD:275368	10/21 (48%)
		zf-H2C2_2	960..985	CDD:290200	9/38 (24%)
		C2H2 Zn finger	976..996	CDD:275368	3/22 (14%)
		C2H2 Zn finger	1004..1023	CDD:275368	5/18 (28%)
MIG3	NP_010945.1	COG5048	1..394	CDD:227381	67/267 (25%)
		C2H2 Zn finger	19..39	CDD:275368	6/19 (32%)
		C2H2 Zn finger	47..69	CDD:275368	10/21 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4354
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950