Protein Alignment Blimp-1 and Prdm4

DIOPT Version :9

• Sequence 1: NP_001261442.1
• Gene: Blimp-1 / 38638
• FlyBaseID: FBgn0035625
• Length: 1216
• Species: Drosophila melanogaster
• Sequence 2: NP_857633.2
• Gene: Prdm4 / 72843
• MGIID: 1920093
• Length: 803
• Species: Mus musculus
• Alignment Length: 955
• Identity: 198/955 - (20%)
• Similarity: 303/955 - (31%)
• Gaps: 354/955 - (37%)

  Fly   295 GEDGKPRYS-MPAPEIP---PDV--AVSHITYVMGLHLPVGAGNGPANGSVAG--SVSGATPPPP 351
            |....|.:| :|||.:|   |::  ::|.:...:.|.||||.|:   .|.:.|  ..:...||||
Mouse    31 GLAASPSHSAIPAPGLPVAIPNLGPSLSSLPSALSLMLPVGIGD---RGVMCGLPERNYTLPPPP 92

  Fly   352 TATPCCRRSSPPAHVSTTTSTCNAHHPHIQHGRHASVIIG-----QDRSP-------MASSDKDT 404
                                     :||::.....:::.|     .||.|       ..:.|.:|
Mouse    93 -------------------------YPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNT 132

  Fly   405 A----GSPLSGLDHQMTPQDGSV-----------RSVRSD--EGYHSNECHE------------- 439
            |    .:| |.||....  :|:|           |||.:.  :..|.|:.||
Mouse   133 ALSITNNP-SALDPYQA--NGNVGLELGIVSIDSRSVNTHGAQSLHPNDGHEVALDTTITMENVS 194

  Fly   440 -----------------DGLT--PPEDSSDSESEHNYVLDCSKKAIAPKETV----IAQAQKPSS 481
                             ||:|  .|:..:.|.|.....:|....::. .|.|    :........
Mouse   195 RVTSPISTDGMAEELTMDGVTGEHPQIPNGSRSHEPLSVDSVSNSLT-AEAVGHGGVIPIHGNGL 258

  Fly   482 SPPAVVMANTTTNSMISHSSPTATPICETDKNEYRKFKVKMPLKYEFKNKTCVKQEPSLKEVDQE 546
            ..|.|:..:...|.:...|..|.:....|.........|.:...:...:...|    ||.||.
Mouse   259 ELPVVMETDHIANRVNGMSDSTLSDSIHTVAMSTNSVSVALSTSHNLASLESV----SLHEVG-- 317

  Fly   547 MSLPQEEEEDQVMHPEPDSICPST-TTHLGDEHMLMMERERERERERIQEREPSNQQPASSTVIV 610
            :||            ||.::...| ...:|..|:.:...........:|..:.::.:...:|:..
Mouse   318 LSL------------EPVAVSSITQEVAMGTGHVDVSSDSLSFVPSSLQMEDSNSNKENMATLFT 370

  Fly   611 L--------------EHNSGGQARTIVPLSKPYYEPDPPGERYMRFGQPSSSIL----------- 650
            :              :|.         |::   :.||.|.|...|...|...:|
Mouse   371 IWCTLCDRAYPSDCPDHG---------PVT---FVPDTPIESRARLSLPKQLVLRQSIVGTDVVG 423

  Fly   651 ----------ETI--------LTSQ--HRLEAA-------------------------------- 663
                      |||        |..|  |.||.|
Mouse   424 VLPLIGVWTAETIPVRTCFGPLIGQQSHSLEVAEWTDKAVNHVWKIYHTGVLEFCIITTDENECN 488

  Fly   664 -----AAAANACRQANAATP-------------PPTSPTEMAYSYKKSQRYGNAVSPD-SSSNLG 709
                 ..|.|...|...|.|             ||.|.....||...:|:.|....|| ...|.|
Mouse   489 WMMFVRKARNREEQNLVAYPHDGKIYFCTSQDIPPESELLFYYSRNYAQQIGVPEHPDVHLCNCG 553

  Fly   710 QNPEQLSSSAVVVGEQEMTRATMIKGECSPPPPSHHHHNVIFSPSRHAAYLGAGEAGGHSPSPGY 774
            :                         |||             |.|...|:| ......|.||.|:
Mouse   554 K-------------------------ECS-------------SYSEFKAHL-TSHIHNHLPSQGH 579

  Fly   775 PGYPHYGAAATSTFHSPPHSSHSPFDRQSNASSGAGSATNLHLLQTSTQMLNHPLMQPLTPLQRL 839
                       |:.|.|.||....: :.|.......|.:.||:     ..:.|..|:|
Mouse   580 -----------SSSHGPSHSKERKW-KCSMCPQAFISPSKLHV-----HFMGHMGMKP------- 620

  Fly   840 SPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSN 904
                                                              ::|:.|.|.|...||
Mouse   621 --------------------------------------------------HKCDFCSKAFSDPSN 635

  Fly   905 LKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHS 969
            |:.||:.|:|::.::|.:|.|||||.|||:.|.::|||||..:||.|.|.|....:||.|:.:|:
Mouse   636 LRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHT 700

  Fly   970 GQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEE 1034
            .::...|..|.:.|.:..|||.|...|...|.|||:.|.|.|::...|..|.||  ||     |.
Mouse   701 QERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKT--CK-----EP 758

  Fly  1035 LAMAAAATSECLDKDHPEPDSREAYEQLTQHMHPAVHPGLRHLSS 1079
            .:.::|...|  |.:..|.|..::.......|..||:.....||:
Mouse   759 SSSSSAQEEE--DDESEEEDLADSMRTEDCRMGSAVYSTDESLSA 801

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Blimp-1	NP_001261442.1	SET	133..260	CDD:214614
		C2H2 Zn finger	892..912	CDD:275368	9/19 (47%)
		zf-H2C2_2	904..929	CDD:290200	11/24 (46%)
		C2H2 Zn finger	920..940	CDD:275368	11/19 (58%)
		zf-H2C2_2	932..957	CDD:290200	13/24 (54%)
		C2H2 Zn finger	948..968	CDD:275368	8/19 (42%)
		zf-H2C2_2	960..985	CDD:290200	7/24 (29%)
		C2H2 Zn finger	976..996	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1004..1023	CDD:275368	6/18 (33%)
Prdm4	NP_857633.2	zf_PR_Knuckle	361..398	CDD:375871	5/48 (10%)
		PR-SET_PRDM4	401..540	CDD:380966	23/138 (17%)
		C2H2 Zn finger	550..569	CDD:275368	9/57 (16%)
		C2H2 Zn finger	595..615	CDD:275368	4/24 (17%)
		zf-C2H2	621..643	CDD:333835	9/21 (43%)
		C2H2 Zn finger	623..643	CDD:275368	9/19 (47%)
		zf-H2C2_2	635..660	CDD:372612	11/24 (46%)
		C2H2 Zn finger	651..671	CDD:275368	11/19 (58%)
		zf-H2C2_2	663..686	CDD:372612	12/22 (55%)
		C2H2 Zn finger	679..699	CDD:275368	8/19 (42%)
		zf-H2C2_2	691..716	CDD:372612	7/24 (29%)
		C2H2 Zn finger	707..727	CDD:275368	7/19 (37%)
		C2H2 Zn finger	735..754	CDD:275368	6/18 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	757..803		11/47 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2461
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810