DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Blimp-1 and CG42726

DIOPT Version :9

Sequence 1:	NP_001261442.1	Gene:	Blimp-1 / 38638	FlyBaseID:	FBgn0035625	Length:	1216	Species:	Drosophila melanogaster
Sequence 2:	NP_732017.3	Gene:	CG42726 / 318709	FlyBaseID:	FBgn0261679	Length:	441	Species:	Drosophila melanogaster

Alignment Length:	353	Identity:	94/353 - (26%)
Similarity:	147/353 - (41%)	Gaps:	83/353 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   881 LKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKP 945
            |||      :.|..|.:.|...|:||.||.:|..:....|:||.|||.|...||:|.|.|..||
  Fly    98 LKK------FNCKECGRRFATSSHLKYHLMSHEKQSKHSCSVCHKSFKQPIVLQRHMLTHNQEK- 155

  Fly   946 HQCDICKKRFSSTSNLKTHLRLHS--GQKPYACDLCPQKFTQFVHLKLHKRLH-TNDRPYVCQGC 1007
            |.|.||:|.|...|:|.:||.:||  |.: :.|:||.:.|....:|..|.|.| .|:..::|:.|
  Fly   156 HLCPICQKVFRRKSSLASHLAIHSDLGLQ-FKCELCSKHFQNKANLNQHLRKHDKNNIRHMCKVC 219

  Fly  1008 DKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDHPEPD----------SREAY--- 1059
            .|.::..:.||.|.|    :.:|.|.:      :.|.| .|.:.:||          :.|.|
  Fly   220 QKSFLRQTTLRLHMK----RHSNRERQ------SCSLC-GKSYNDPDALGRHLRQHKTAERYRCI 273

  Fly  1060 ---------EQLTQHMHPAVHPGLRHLSSGGQSPPRLIPLGNHMAPQQQSHQQQQQQHQQQGVPP 1115
                     :.:.:|:. ::|||....|:.....||             |..|:....:::....
  Fly   274 QCDITINRKDNMLRHLR-SMHPGCAFASTVEMVTPR-------------SSAQEATTAEERPSQT 324

  Fly  1116 PHLLMTQHSVGPA-PMLLTTASQLPPPPPHHQQNSPSRLLQHGHAHPLQMQQQQQQQQQHSPKGL 1179
            ........|||.. |::|..::.||...|..|       ::.|.|.|           :|.|..
  Fly   325 VRYNSVIQSVGNVEPVMLLQSTPLPSQLPELQ-------MEKGKAVP-----------EHLPLP- 370

  Fly  1180 KSLPESGVYLHGQHV-----QAQESRPS 1202
            ..:||..|.|:.:.:     :...|.||
  Fly   371 DVMPEENVQLYRKIILDLDNEEYSSEPS 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Blimp-1	NP_001261442.1	SET	133..260	CDD:214614
		C2H2 Zn finger	892..912	CDD:275368	8/19 (42%)
		zf-H2C2_2	904..929	CDD:290200	11/24 (46%)
		C2H2 Zn finger	920..940	CDD:275368	11/19 (58%)
		zf-H2C2_2	932..957	CDD:290200	13/24 (54%)
		C2H2 Zn finger	948..968	CDD:275368	9/19 (47%)
		zf-H2C2_2	960..985	CDD:290200	10/26 (38%)
		C2H2 Zn finger	976..996	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1004..1023	CDD:275368	6/18 (33%)
CG42726	NP_732017.3	C2H2 Zn finger	74..94	CDD:275368
		C2H2 Zn finger	103..123	CDD:275368	8/19 (42%)
		COG5048	<112..288	CDD:227381	58/188 (31%)
		C2H2 Zn finger	131..151	CDD:275368	11/19 (58%)
		Chordopox_A33R	151..>254	CDD:283591	37/115 (32%)
		C2H2 Zn finger	158..178	CDD:275368	9/19 (47%)
		C2H2 Zn finger	187..207	CDD:275368	7/19 (37%)
		C2H2 Zn finger	216..236	CDD:275368	7/23 (30%)
		C2H2 Zn finger	244..264	CDD:275368	5/20 (25%)
		C2H2 Zn finger	272..290	CDD:275368	1/17 (6%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457160
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930