DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Blimp-1 and set-17

DIOPT Version :9

Sequence 1:	NP_001261442.1	Gene:	Blimp-1 / 38638	FlyBaseID:	FBgn0035625	Length:	1216	Species:	Drosophila melanogaster
Sequence 2:	NP_001317778.1	Gene:	set-17 / 174425	WormBaseID:	WBGene00011887	Length:	277	Species:	Caenorhabditis elegans

Alignment Length:	208	Identity:	52/208 - (25%)
Similarity:	83/208 - (39%)	Gaps:	52/208 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 VYLVPDVQAERGLPNR---ADKTLPRSLTLKSSMVYSTPNVKTEGVWSSGVIPRGTRFGPFEGIP 163
            ::.:||...:|...:.   :.:|||....::.|.:   ||... ||.:...||.|..|||::| .
Worm   108 LFKIPDRVLKRDESSNLSFSQQTLPILFRIEESKL---PNAGL-GVIAEVFIPVGMVFGPYKG-R 167

  Fly   164 TSNYPNDKNKARYFWRVQGTRHITYGNIKIFKDDDYYYLDGSDRSQSNWMRYVASAYSLSVMNLV 228
            ......|..|..|.|.::             ..|..:|:||||..:|||:||:.|.......|::
Worm   168 RCQKKTDFYKDGYAWLIK-------------SGDKRFYIDGSDAERSNWLRYINSPRFEDEQNML 219

  Fly   229 ACQHQENIYFYTTRDILPNEELMVWYCKDFASRLGYDVDPETTIFGACKQAVEAEEEADEEEEEA 293
            |.|....|::...:.|..|:||:|||...:.:                              |..
Worm   220 AFQTNGKIFYRVIKPIRINQELLVWYGSSYGN------------------------------EFV 254

  Fly   294 EGEDGKPRYSMPA 306
            |.|:|. :|..||
Worm   255 ESENGN-KYKKPA 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Blimp-1	NP_001261442.1	SET	133..260	CDD:214614	38/126 (30%)
		C2H2 Zn finger	892..912	CDD:275368
		zf-H2C2_2	904..929	CDD:290200
		C2H2 Zn finger	920..940	CDD:275368
		zf-H2C2_2	932..957	CDD:290200
		C2H2 Zn finger	948..968	CDD:275368
		zf-H2C2_2	960..985	CDD:290200
		C2H2 Zn finger	976..996	CDD:275368
		C2H2 Zn finger	1004..1023	CDD:275368
set-17	NP_001317778.1	PHD_SF	82..>113	CDD:419867	0/4 (0%)
set-17	NP_001317778.1	PR-SET_PRDM7_9	128..255	CDD:380970	43/174 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2461
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810