DRSC/TRiP Functional Genomics Resources

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Protein Alignment Blimp-1 and PRDM7

DIOPT Version :9

Sequence 1:NP_001261442.1 Gene:Blimp-1 / 38638 FlyBaseID:FBgn0035625 Length:1216 Species:Drosophila melanogaster
Sequence 2:NP_001091643.1 Gene:PRDM7 / 11105 HGNCID:9351 Length:492 Species:Homo sapiens


Alignment Length:305 Identity:76/305 - (24%)
Similarity:124/305 - (40%) Gaps:67/305 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 PQQQPQNP--------QEQQSG----------AIMKAANQPHHPAHSHPLNHPHPHQHAQPHPHP 57
            |:||.:.|        .:.|.|          ::.:.:..|      :.||.....|..:|...|
Human    97 PRQQVKPPWMAFRGEQSKHQKGMPKASFNNESSLRELSGTP------NLLNTSDSEQAQKPVSPP 155

  Fly    58 ------HPHPHHKLSARRARSRSRSRSPTPDGNQDY-DVTRMREEDF-----------ERLAVY- 103
                  ..|...||..||..:..:..|........| :::..:::|:           :..|.: 
Human   156 GEASTSGQHSRLKLELRRKETEGKMYSLRERKGHAYKEISEPQDDDYLYCEMCQNFFIDSCAAHG 220

  Fly   104 ---LVPDVQAERGLPNRADKTLPRSLTLKSSMVYSTPNVKTEGVWS-SGVIPRGTRFGPFEGIPT 164
               .|.|...::|.|||:..:||..|.:..|.:   |.... |||: :..:|.|..|||:||..|
Human   221 PPTFVKDSAVDKGHPNRSALSLPPGLRIGPSGI---PQAGL-GVWNEASDLPLGLHFGPYEGRIT 281

  Fly   165 SNYPNDKNKARYFWRVQGTRHITYGNIKIFKDDDYYYLDGSDRSQSNWMRYVASAYSLSVMNLVA 229
            .:  .:...:.|.|.:...|:.            |.|:||.|:|.:||||||..|......||||
Human   282 ED--EEAANSGYSWLITKGRNC------------YEYVDGKDKSSANWMRYVNCARDDEEQNLVA 332

  Fly   230 CQHQENIYFYTTRDILPNEELMVWYCKDFASRLGY--DVDPETTI 272
            .|:...|::.|.|.|.|..||:||...::...||.  .::|..::
Human   333 FQYHRQIFYRTCRVIRPGCELLVWSGDEYGQELGIRSSIEPAESL 377

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Blimp-1NP_001261442.1 SET 133..260 CDD:214614 42/127 (33%)
C2H2 Zn finger 892..912 CDD:275368
zf-H2C2_2 904..929 CDD:290200
C2H2 Zn finger 920..940 CDD:275368
zf-H2C2_2 932..957 CDD:290200
C2H2 Zn finger 948..968 CDD:275368
zf-H2C2_2 960..985 CDD:290200
C2H2 Zn finger 976..996 CDD:275368
C2H2 Zn finger 1004..1023 CDD:275368
PRDM7NP_001091643.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..22
KRAB 27..85 CDD:214630
KRAB 27..64 CDD:279668
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 111..179 13/73 (18%)
SSXRD 171..201 CDD:286586 4/29 (14%)
SET 246..364 CDD:214614 44/135 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2461
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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