DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Blimp-1 and Zfp683

DIOPT Version :9

Sequence 1:	NP_001261442.1	Gene:	Blimp-1 / 38638	FlyBaseID:	FBgn0035625	Length:	1216	Species:	Drosophila melanogaster
Sequence 2:	XP_002729595.3	Gene:	Zfp683 / 100359438	RGDID:	2323855	Length:	476	Species:	Rattus norvegicus

Alignment Length:	482	Identity:	151/482 - (31%)
Similarity:	200/482 - (41%)	Gaps:	140/482 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   560 HPEPDSICPSTTTHLGDEHMLMMERERERERERIQEREPSNQQPASSTVIVLEHNSGGQARTIVP 624
            |.:.|.:|.:.|:....:.|      ..|:....:...|....||.|:::....   |....:..
  Rat    33 HYQDDQVCSADTSQPLPDTM------DARDLPWSERMCPLPLAPAKSSLLACPE---GLDLRLCA 88

  Fly   625 LSKPYYEPDPPGERYMRFGQPSSSILETILTSQHRLEAAAAAANACRQANAATPPPTSPTEMAYS 689
            |.|     .|.|......|:.:|                          |....||:       .
  Rat    89 LQK-----TPLGRASQDLGEDAS--------------------------NTRQQPPS-------L 115

  Fly   690 YKKSQRYGNAVS--PDSSSNLGQNPEQLSSSAVVVGEQEMTRATMIKGECSP-------PP---- 741
            ||.|.......:  |.:...:|..||:.:..|:.........|.:.:...||       ||
  Rat   116 YKASTDIEKLTTKDPRNREEMGNQPERGAHPALPPHTSSFPEAGLDRKSLSPLTFWPWLPPTFIS 180

  Fly   742 ---PSHHHHNVIFSPSRHAAYLGAGEAGGHSPSPGYPGYPHYGAAATSTFHSPPHSSHSPF---- 799
               |.|.:                         |.:||||.:......|:.:.| |:..|:
  Rat   181 KETPIHIY-------------------------PIFPGYPLWPLPYLFTYGTQP-SAQCPYLFML 219

  Fly   800 --DRQSNASSGAG-----SATNLHLLQTSTQML--------NHPL---------MQPLTPLQR-- 838
              |.....::|||     :....|..|..|.:|        .|.|         ...|||.|.
  Rat   220 PPDSTYPTTTGAGLFMTANGPGPHTPQEKTLLLYSGAFQSAGHTLYSQVGSRSSRDALTPGQAGV 284

  Fly   839 LSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLS 903
            .:|.|.:.|.|.:                     |..:|||||||::||:.||||||.|.|||||
  Rat   285 TAPARQAVPGSRA---------------------GVIALPYPLKKENGKILYECNVCGKNFGQLS 328

  Fly   904 NLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLH 968
            |||||||.|||||||:|.:|.|.|||||||||||||||||:||||.:|.|||||.||||||||||
  Rat   329 NLKVHLRVHSGERPFQCALCQKRFTQLAHLQKHHLVHTGERPHQCQVCHKRFSSPSNLKTHLRLH 393

  Fly   969 SGQKPYACDLCPQKFTQFVHLKLHKRL 995
            ||.:|:.|.:||...|:.|:.|||.||
  Rat   394 SGARPFQCSICPSHLTRNVYPKLHPRL 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Blimp-1	NP_001261442.1	SET	133..260	CDD:214614
		C2H2 Zn finger	892..912	CDD:275368	17/19 (89%)
		zf-H2C2_2	904..929	CDD:290200	18/24 (75%)
		C2H2 Zn finger	920..940	CDD:275368	15/19 (79%)
		zf-H2C2_2	932..957	CDD:290200	20/24 (83%)
		C2H2 Zn finger	948..968	CDD:275368	15/19 (79%)
		zf-H2C2_2	960..985	CDD:290200	15/24 (63%)
		C2H2 Zn finger	976..996	CDD:275368	10/20 (50%)
		C2H2 Zn finger	1004..1023	CDD:275368
Zfp683	XP_002729595.3	COG5048	<310..421	CDD:227381	81/111 (73%)
		C2H2 Zn finger	317..337	CDD:275368	17/19 (89%)
		C2H2 Zn finger	345..365	CDD:275368	15/19 (79%)
		C2H2 Zn finger	373..393	CDD:275368	15/19 (79%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D233655at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010