Protein Alignment TM9SF3 and TMN3

DIOPT Version :9

• Sequence 1: NP_647979.1
• Gene: TM9SF3 / 38635
• FlyBaseID: FBgn0035622
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_011038.3
• Gene: TMN3 / 856849
• SGDID: S000000915
• Length: 706
• Species: Saccharomyces cerevisiae
• Alignment Length: 663
• Identity: 154/663 - (23%)
• Similarity: 257/663 - (38%)
• Gaps: 172/663 - (25%)

  Fly    58 QETYAYFSLPFCSGQKSSISHYHETLSEALQGVELEFSGYEMEFKSDAPKSVICMVTLQEESAKA 122
            |..|||:.|||...........|.:|:|.::|.....|.|:::|..|.|...:|.....:|..:.
Yeast    76 QLPYAYYDLPFTCPPTMHKKPLHLSLNEIIRGDRKWESDYKLKFGEDNPCETLCARKTTKEGMQT 140

  Fly   123 FTYAVKNEYWYQMYID---------------------GLPIWGKVGERDERDGKYYIFTH----- 161
            ....|:..|..|..||                     |.|:    |..|....|.|:..|
Yeast   141 LDKLVREGYVVQWLIDDELPAATTFISTTDHKKYYASGFPL----GFIDPDTDKTYLHNHVMLVI 201

  Fly   162 --------KKFDIG-------------------YNGQQIVDITLTTEGREELKPGSHINFSYEVN 199
                    |...:|                   |...:||    ..|...||   :::.|:|.|.
Yeast   202 RFHASDNDKNTIVGFEVYPRSVSDYHCPGASKNYEQYEIV----IPEDENEL---TYLPFTYSVY 259

  Fly   200 WKPS-KVEFKNRFDKYLDPNFFQH----RIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYA--- 256
            |:.. :|::.:|:|.:|:......    :.||.|:.||..:|:.:..:..:|.:|.:..|.:
Yeast   260 WREEFEVDWNHRWDYFLNAGELSDEQSIQFHWMSLANSVGIVLSISFITLIIYVRVMYTDKSNSK 324

  Fly   257 --RYSKDEEIDDMERDLGDE-YG----------WKQVHGDVFRSPPNTLLFSALVGAGYQLISVV 308
              :|..:.|..:.|.||.|: ||          |.|      ...||      |.|....::.|.
Yeast   325 SPKYMINIEGIETEDDLDDDKYGKYSVYTVAKDWIQ------NGRPN------LFGLKVLILLVS 377

  Fly   309 FCV-IMFAIVG---------ELYTERGSMLSTAIFVYAATSPINGYFGGSL------------YA 351
            |.| .:|.|:|         :|:..|.|:|:.||..:...:.:..:.|..|            |
Yeast   378 FGVQFLFTIIGSLTISCSMNKLHNVRNSVLTMAILFFVLGAFMASFVGTRLSMVTKTKRTKANY- 441

  Fly   352 RLGGRMWIR--QMLVSAFTVPVAVCGTA---------FLINFIAIGYHASRAIPFGTMVAVTCIC 405
             |....:::  :.....||:   :||::         ||:|.|...:.::.|:||.|:|....|.
Yeast   442 -LDDNRYLKDYKKFSPIFTI---LCGSSLPGIVMVSTFLLNSIVWAHDSTSALPFKTIVFFMSIY 502

  Fly   406 LFVILPLTLVGTVVGRNL-----------------DGQPDFPCRVNAVPRPIPEKKWYMEPLII- 452
            ..|.:||:|.|.:|..|:                 ||...|          :|:.:....||:.
Yeast   503 FIVCIPLSLFGGIVANNIPLPQYWLSGITKDESNSDGNGLF----------VPKSRAKFNPLVYC 557

  Fly   453 -VLLGGVLPFGSIFIEMYFIFTSFWAYK--IYYVYGFMLLVFSILTVVTVCVTIVCTYFLLN--A 512
             :.|.|:.|...|::||.:::.|.|..|  .||.|||:.|...:|.|:|:.::|:.:|.|:.  .
Yeast   558 GIYLCGIFPLLVIYVEMQYVYKSLWLEKTTFYYFYGFLFLSIILLCVLTMEISIIGSYLLMRFCF 622

  Fly   513 ED----YRWQWTSFMAAGSTSIYVYAYSFYYFFFKTKMFGLFQTAFYFGYMALFSGALGIICGTV 573
            ||    ..|:|..|....|..:|:..||.||.|....:.|.........|..:|:....:..|.:
Yeast   623 EDKVVRNNWRWKCFEMGFSGGVYMELYSLYYIFAVLNIHGFSSILISICYSLIFNVMCSLGLGAL 687

  Fly   574 GYVGTNLFVRKIY 586
            .|:..:.|:.|||
Yeast   688 SYLTASWFINKIY 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF3	NP_647979.1	EMP70	60..530	CDD:281048	138/603 (23%)
TMN3	NP_011038.3	EMP70	78..663	CDD:397233	144/622 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820