Protein Alignment TM9SF3 and TMN2

DIOPT Version :9

• Sequence 1: NP_647979.1
• Gene: TM9SF3 / 38635
• FlyBaseID: FBgn0035622
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_010392.1
• Gene: TMN2 / 851685
• SGDID: S000002514
• Length: 672
• Species: Saccharomyces cerevisiae
• Alignment Length: 676
• Identity: 180/676 - (26%)
• Similarity: 304/676 - (44%)
• Gaps: 113/676 - (16%)

  Fly    20 LIASCYVSLSQADE----HNHKYNDREEVVLWMNTVGP--YHNRQE---------------TYAY 63
            |:..||.:|::...    ....|:..:|:.|.:|.:.|  |...|:               :|.|
Yeast     7 LLIYCYATLTKGFSLPGLSPTTYHSGDEIPLLVNRLTPSIYFQHQDEEGNDVSGDKEHFLYSYDY 71

  Fly    64 FSLPFCSGQKSSISHYHETLSEALQGVELEFSGYEMEFKSDAPKSVICMVTLQEESAKAFTYAVK 128
            ::..|...:...:....|:|...:.|..:..|.:::....:.....:|..|:..:.||.....:|
Yeast    72 YNKRFHFCRPEHVEKQPESLGSVIFGDRIYNSPFQLNMLEEKECVALCKSTIPGKDAKFINTLIK 136

  Fly   129 NEYWYQMYIDGLPIWGK----------------VGERDER---DGKY------------------ 156
            :.::....:||||...|                :|..|.:   |||.
Yeast   137 SGFFQNWLVDGLPAARKAYDSRTKTNYYGTGFELGFTDVKQTVDGKAVPSTMEELTSEASNEDVI 201

  Fly   157 --------------------YIFTHKKFDI-------GYNGQQIVDITLTTEGREELKPG----- 189
                                |...|  |||       |.:..::|.:.:.....|...||
Yeast   202 LDARLPKNVKPNLVKTVELPYFVNH--FDIEVEFHDRGNDNYRVVGVIVNPVSIERSSPGACSTT 264

  Fly   190 -----------SHINFSYEVNWKPSKVEFKNRFDKYLDPNFFQHRIHWFSIFNSFMMVIFLVGLV 243
                       :.:.|:|.|.:..|...:..|:||||  :.:..:|.|||:.|..::||.|..:|
Yeast   265 GKPLILDEDKDNEVYFTYSVKFVASDTVWATRWDKYL--HIYDPQIQWFSLINFSVIVILLSSVV 327

  Fly   244 SMILMRTLRKDYARYSKDEEIDDMERDLGDEYGWKQVHGDVFRSPPNTLLFSALVGAGYQLISVV 308
            ...|:|.|:.|.|||:   |: :::.:..::.|||..||||||:|..::|.|.|||:|.||..:|
Yeast   328 MHSLLRALKSDLARYN---EL-NLDNEFHEDSGWKLGHGDVFRTPSKSMLLSILVGSGMQLFLMV 388

  Fly   309 FCVIMFAIVGELY-TERGSMLSTAIFVYAATSPINGYFGGSLYARLGGRMWIRQMLVSAFTVPVA 372
            .|.|.||.||.:. ..|||:.:....:||....:..|....:|....|..|...|:::...:|.|
Yeast   389 MCSIFFAAVGLVSPVSRGSLPTVMFVLYALFGFVGSYASMGVYKFFRGPYWKANMILTPILLPGA 453

  Fly   373 VCGTAFLINFIAIGYHASRAIPFGTMVAVTCICLFVILPLTLVGTVVGRNLDGQPDFPCRVNAVP 437
            :.....::||..:..|:|..||..::..:..:...|.:||:..|::|........:.|.:.|.:.
Yeast   454 IFLLIVIMNFFLLFAHSSGVIPARSLFFIILLWFLVSVPLSFAGSIVAHKQCNWDEHPTKTNQIA 518

  Fly   438 RPIPEKKWYMEPLIIVLLGGVLPFGSIFIEMYFIFTSFWAYKIYYVYGFMLLVFSILTVVTVCVT 502
            |.||.:.||:......|:.|:..||||.:|:|||::|.|..||:|::||:|..|.:||:.|..||
Yeast   519 RQIPYQPWYLRTAQATLIAGIFSFGSIAVELYFIYSSLWFNKIFYMFGFLLFSFLLLTLTTSLVT 583

  Fly   503 IVCTYFLLNAEDYRWQWTSFMAAG-STSIYVYAYSFYYFFFKTKMFGLFQTAFYFGYMALFSGAL 566
            |:.||:.|..|::.|||.||:..| ..|||.:.:|.  .|.|.|:.|:.....|.||..:.|...
Yeast   584 ILITYYSLCLENWLWQWRSFIIGGLGCSIYTFIHSI--LFTKFKLGGVITVVLYLGYSLIISALC 646

  Fly   567 GIICGTVGYVGTNLFVRKIYSNVKID 592
            .::.|.:|:..:..|:|||||.:|::
Yeast   647 CVVTGAIGFFSSMFFIRKIYSAIKVE 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF3	NP_647979.1	EMP70	60..530	CDD:281048	148/551 (27%)
TMN2	NP_010392.1	EMP70	68..629	CDD:397233	155/570 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820