Protein Alignment TM9SF3 and EMP70

DIOPT Version :9

• Sequence 1: NP_647979.1
• Gene: TM9SF3 / 38635
• FlyBaseID: FBgn0035622
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_013184.1
• Gene: EMP70 / 850772
• SGDID: S000004073
• Length: 667
• Species: Saccharomyces cerevisiae
• Alignment Length: 653
• Identity: 183/653 - (28%)
• Similarity: 300/653 - (45%)
• Gaps: 116/653 - (17%)

  Fly    38 YNDREEVVLWMNTVGP---YHNRQE----------------TYAYFSLPFCSGQKSSISHYHETL 83
            |.:.:.:.|.:|.:.|   |.::.|                .|.|....||..:|  :....|:|
Yeast    33 YRENDNIPLLVNHLTPSMNYQHKDEDGNNVSGDKENFLYSYDYYYNRFHFCQPEK--VEKQPESL 95

  Fly    84 SEALQGVELEFSGYEMEFKSDAPKSVICMVTLQEESAKAFTYAVKNEYWYQMYIDGLPIWGKVGE 148
            ...:.|..:..|.:::....:.....:|...:..:.||.....:||.::....|||||     ..
Yeast    96 GSVIFGDRIYNSPFQLNMLQEKECESLCKTVIPGDDAKFINKLIKNGFFQNWLIDGLP-----AA 155

  Fly   149 RDERDGKYYI-FTHKKFDIGY-NGQQIVDITLTTEGRE------ELK------------------ 187
            |:..||:... |....|::|: ...|..||..|.:|.|      ||:
Yeast   156 REVYDGRTKTSFYGAGFNLGFVQVTQGTDIEATPKGAETTDKDVELETRNDRNMVKTYELPYFAN 220

  Fly   188 --------------------------------PG----------------SHINFSYEVNWKPSK 204
                                            ||                :.:.|:|.|.:..|.
Yeast   221 HFDIMIEYHDRGEGNYRVVGVIVEPVSIKRSSPGTCETTGSPLMLDEGNDNEVYFTYSVKFNESA 285

  Fly   205 VEFKNRFDKYL---DPNFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKDEEIDD 266
            ..:..|:||||   ||:     |.|||:.|..::|:.|..:|...|:|.|:.|:|||: :..:||
Yeast   286 TSWATRWDKYLHVYDPS-----IQWFSLINFSLVVVLLSSVVIHSLLRALKSDFARYN-ELNLDD 344

  Fly   267 MERDLGDEYGWKQVHGDVFRSPPNTLLFSALVGAGYQLISVVFCVIMFAIVGELY-TERGSMLST 330
               |..::.|||..||||||||..:|..|.|||:|.||..:|.|.|.||.:|.|. :.|||:.:.
Yeast   345 ---DFQEDSGWKLNHGDVFRSPSQSLTLSILVGSGVQLFLMVTCSIFFAALGFLSPSSRGSLATV 406

  Fly   331 AIFVYAATSPINGYFGGSLYARLGGRMWIRQMLVSAFTVPVAVCGTAFLINFIAIGYHASRAIPF 395
            ...:||....:..|....:|....|..|...::::...||.|:......:||..:..|:|..||.
Yeast   407 MFILYALFGFVGSYTSMGIYKFFNGPYWKANLILTPLLVPGAILLIIIALNFFLMFVHSSGVIPA 471

  Fly   396 GTMVAVTCICLFVILPLTLVGTVVGRNLDGQPDFPCRVNAVPRPIPEKKWYMEPLIIVLLGGVLP 460
            .|:..:..:.....:||:..|:::.|......:.|.:.|.:.|.||.:.||::.:...|:.|:.|
Yeast   472 STLFFMVFLWFLFSIPLSFAGSLIARKRCHWDEHPTKTNQIARQIPFQPWYLKTIPATLIAGIFP 536

  Fly   461 FGSIFIEMYFIFTSFWAYKIYYVYGFMLLVFSILTVVTVCVTIVCTYFLLNAEDYRWQWTSFMAA 525
            ||||.:|:|||:||.|..||:|::||:...|.:||:.:..|||:.||..|..|:::|||..|:..
Yeast   537 FGSIAVELYFIYTSLWFNKIFYMFGFLFFSFLLLTLTSSLVTILITYHSLCLENWKWQWRGFIIG 601

  Fly   526 GS-TSIYVYAYSFYYFFFKTKMFGLFQTAFYFGYMALFSGALGIICGTVGYVGTNLFVRKIYSNV 589
            |: .::||:.:|.  .|.|.|:.|......|.||.::.|....::.|::|::.:.||||||||::
Yeast   602 GAGCALYVFIHSI--LFTKFKLGGFTTIVLYVGYSSVISLLCCLVTGSIGFISSMLFVRKIYSSI 664

  Fly   590 KID 592
            |:|
Yeast   665 KVD 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF3	NP_647979.1	EMP70	60..530	CDD:281048	154/548 (28%)
EMP70	NP_013184.1	EMP70	72..624	CDD:397233	160/569 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820