DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TM9SF3 and TMN1

DIOPT Version :9

Sequence 1:	NP_647979.1	Gene:	TM9SF3 / 38635	FlyBaseID:	FBgn0035622	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_563881.1	Gene:	TMN1 / 837638	AraportID:	AT1G10950	Length:	589	Species:	Arabidopsis thaliana

Alignment Length:	584	Identity:	315/584 - (53%)
Similarity:	415/584 - (71%)	Gaps:	7/584 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 AICLCLLIASCYVSLSQADEHNHKYNDREEVVLWMNTVGPYHNRQETYAYFSLPFCSGQKSSISH 78
            |:.:.||:.| .::.:.|.:.:|||...|:|.||:|.||||:|.||||.|:|||||....::: |
plant     8 AVLVFLLLVS-LLTPTFASDSDHKYQAEEQVTLWVNKVGPYNNPQETYNYYSLPFCRPSGNNV-H 70

  Fly    79 YHETLSEALQGVELEFSGYEMEFKSDAPKSVICMVTLQEESAKAFTYAVKNEYWYQMYIDGLPIW 143
            ....|.|.|.|.||..|...::|..:..:||||.:.|.|...|.|..|:::.||::.::|.||:|
plant    71 KWGGLGEVLGGNELIDSEIAIKFMKNVERSVICPLELDEAKVKHFKDAIESSYWFEFFMDDLPLW 135

  Fly   144 GKVGE----RDERDGKYYIFTHKKFDIGYNGQQIVDITLTTEGREELKPGSHINFSYEVNWKPSK 204
            |.|||    ::..:||:.::|||...:.||..||:.:.||.:....|:.|..::.:|.|.|.|:.
plant   136 GFVGELHPDKNSENGKHVLYTHKNIVVKYNKDQIIHVNLTQDNPRPLEAGKKMDLTYSVQWIPTN 200

  Fly   205 VEFKNRFDKYLDPNFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSK-DEEIDDME 268
            |.|..|||.|||..||:|:||||||||||||||||.||||||||||||.|||:|:: |::::.:|
plant   201 VTFARRFDVYLDYPFFEHQIHWFSIFNSFMMVIFLTGLVSMILMRTLRNDYAKYAREDDDLESLE 265

  Fly   269 RDLGDEYGWKQVHGDVFRSPPNTLLFSALVGAGYQLISVVFCVIMFAIVGELYTERGSMLSTAIF 333
            ||:.:|.|||.|||||||...:.:|.||:||.|.||..:|..||:.||||.||..||::::|.|.
plant   266 RDVSEESGWKLVHGDVFRPASSLVLLSAVVGTGAQLALLVLLVILMAIVGTLYVGRGAIVTTFIV 330

  Fly   334 VYAATSPINGYFGGSLYARLGGRMWIRQMLVSAFTVPVAVCGTAFLINFIAIGYHASRAIPFGTM 398
            .||.||.::||..|.:|:|.||:.||:.|:::|...|....|..||:|.|||.|.:..|||||||
plant   331 CYALTSFVSGYVSGGMYSRSGGKHWIKCMVLTASLFPFLCFGIGFLLNTIAIFYGSLAAIPFGTM 395

  Fly   399 VAVTCICLFVILPLTLVGTVVGRNLDGQPDFPCRVNAVPRPIPEKKWYMEPLIIVLLGGVLPFGS 463
            |.|..|..|:..||.|:|||||||..|.|:.||||..:||||||||||:.|.::.|:||:|||||
plant   396 VVVFVIWGFISFPLALLGTVVGRNWSGAPNNPCRVKTIPRPIPEKKWYLTPSVVSLMGGLLPFGS 460

  Fly   464 IFIEMYFIFTSFWAYKIYYVYGFMLLVFSILTVVTVCVTIVCTYFLLNAEDYRWQWTSFMAAGST 528
            |||||||:|||||.||:|||||||||||.||.:||||||||.||||||||:|.||||||.:|.||
plant   461 IFIEMYFVFTSFWNYKVYYVYGFMLLVFVILVIVTVCVTIVGTYFLLNAENYHWQWTSFFSAAST 525

  Fly   529 SIYVYAYSFYYFFFKTKMFGLFQTAFYFGYMALFSGALGIICGTVGYVGTNLFVRKIYSNVKID 592
            ::|||.||.||::.||||.|.|||:|||||..:|...|||:||.|||:|:|||||:||.|:|.|
plant   526 AVYVYLYSIYYYYVKTKMSGFFQTSFYFGYTMMFCLGLGILCGAVGYLGSNLFVRRIYRNIKCD 589

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF3	NP_647979.1	EMP70	60..530	CDD:281048	255/474 (54%)
TMN1	NP_563881.1	EMP70	54..526	CDD:397233	253/472 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	549	1.000	Domainoid score	I53
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10588
Inparanoid	1	1.050	651	1.000	Inparanoid score	I169
OMA	1	1.010	-	-		QHG53553
OrthoDB	1	1.010	-	-		D641127at2759
OrthoFinder	1	1.000	-	-		FOG0005862
OrthoInspector	1	1.000	-	-		oto3436
orthoMCL	1	0.900	-	-		OOG6_104089
Panther	1	1.100	-	-	O	PTHR10766
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4863
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840