DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TM9SF3 and AT2G24170

DIOPT Version :9

Sequence 1:	NP_647979.1	Gene:	TM9SF3 / 38635	FlyBaseID:	FBgn0035622	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_179994.2	Gene:	AT2G24170 / 816951	AraportID:	AT2G24170	Length:	637	Species:	Arabidopsis thaliana

Alignment Length:	594	Identity:	199/594 - (33%)
Similarity:	316/594 - (53%)	Gaps:	68/594 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 QETYAYFSLPFCSGQKSSISHYHETLSEALQGVELEFSGYEMEFKSDAPKSVICMVTLQEESAKA 122
            |..|:|:|||:|  :...|....|.|.|.|:|..:|.|.:..:.:.....:.:|.|.|.:::|||
plant    53 QLPYSYYSLPYC--RPEHIVDSAENLGEVLRGDRIENSPFVFKMRESQMCAAVCRVKLDKKTAKA 115

  Fly   123 FTYAVKNEYWYQMYIDGLPIWGKVGERDE---------------------RDGKYYIFTHKKFDI 166
            |...:.:||...|.:|.||:...|...|:                     ::.||:|..|..|.:
plant   116 FKEKIADEYRVNMILDNLPLVVPVQRPDQDNVVVYQHGFHVGLKGIFAGKKEEKYFIHNHLTFTV 180

  Fly   167 GYN-------------------------GQQIVDITLTT------------EGREELKPGSHINF 194
            .|:                         ||......|||            |..:|::.|:.|.|
plant   181 RYHRDIQTDSSRIVGFEVKPFSVKHEYEGQWNEKARLTTCDPHTKRAVTNSESPQEVEEGNEIIF 245

  Fly   195 SYEVNWKPSKVEFKNRFDKYLDPNFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYS 259
            :|:|:::.|:|::.:|:|.||  .....:||||||.||.|:|:||.|:|:||::|||.:|.:.|:
plant   246 TYDVDFQESEVKWASRWDTYL--LMADDQIHWFSIVNSMMIVLFLSGMVAMIMLRTLYRDISNYN 308

  Fly   260 KDEEIDDMERDLGDEYGWKQVHGDVFRSPPNTLLFSALVGAGYQLISVVFCVIMFAIVGELY-TE 323
               :::..|..| :|.|||.|||||||.|.|..|.....|.|.|...::...::||.:|.|. :.
plant   309 ---QLESHEEAL-EETGWKLVHGDVFRPPTNPELLCVYAGTGVQCFGMILVTMIFACLGFLSPSN 369

  Fly   324 RGSMLSTAIFVYAATSPINGYFGGSLYARLGGRMWIRQMLVSAFTVPVAVCGTAFLINFIAIGYH 388
            ||.:::..:.::.....:.||....||..|.|..|.|..|.:||..|..|....|::|.|..|..
plant   370 RGGLMTAMLLLWVFMGLLAGYASSRLYKTLRGTEWKRNALKTAFMFPATVFVAFFVLNAIIWGQK 434

  Fly   389 ASRAIPFGTMVAVTCICLFVILPLTLVGTVVGRNLDGQPDFPCRVNAVPRPIPEKKWYMEPLIIV 453
            :|.|:|||||.|:..:...:.:||..:|..:|..... |:.|.:.|.:||.||.:.|||.|:..:
plant   435 SSGAVPFGTMFALVVLWFGISVPLVFIGGYIGFRKPA-PEDPVKTNKIPRQIPTQAWYMNPIFSI 498

  Fly   454 LLGGVLPFGSIFIEMYFIFTSFWAYKIYYVYGFMLLVFSILTVVTVCVTIVCTYFLLNAEDYRWQ 518
            |:||:||||::|||::||.||.|.::.||::||:.:||.||.:....:|:|..||.|.:|||:|.
plant   499 LIGGILPFGAVFIELFFILTSIWLHQFYYIFGFLFIVFIILIITCAEITVVLCYFQLCSEDYQWW 563

  Fly   519 WTSFMAAGSTSIYVYAYSFYYFFFKTKMFGLFQTAFYFGYMALFSGALGIICGTVGYVGTNLFVR 583
            |.|::.:||:::|::.|:.:||:.|.::..|.....|||||.:.|....:..|.:|:.....|.|
plant   564 WRSYLTSGSSAVYLFLYAVFYFYTKLEITKLVSAVLYFGYMLIVSYVFFVFTGAIGFYACFWFTR 628

  Fly   584 KIYSNVKID 592
            .|||:||||
plant   629 LIYSSVKID 637

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF3	NP_647979.1	EMP70	60..530	CDD:281048	175/528 (33%)
AT2G24170	NP_179994.2	EMP70	55..594	CDD:367285	180/547 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoDB	1	1.010	-	-		D641127at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830