Protein Alignment TM9SF3 and Tm9sf2

DIOPT Version :9

• Sequence 1: NP_647979.1
• Gene: TM9SF3 / 38635
• FlyBaseID: FBgn0035622
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_542123.3
• Gene: Tm9sf2 / 68059
• MGIID: 1915309
• Length: 662
• Species: Mus musculus
• Alignment Length: 634
• Identity: 202/634 - (31%)
• Similarity: 317/634 - (50%)
• Gaps: 100/634 - (15%)

  Fly    37 KYND-REEVVLWMN------TVGPYHNRQETYAYFSLPFCSGQKSSISHYHETLSEALQGVELEF 94
            |.|: :.::.|::|      :|.||.       |.:..||  |.|......|.|.:.|.|..:|.
Mouse    51 KSNECKADIELFVNRLDSVESVLPYE-------YTAFDFC--QASEGKRPSENLGQVLFGERIEP 106

  Fly    95 SGYEMEFKSDAPKSVICMVTLQEESA---KAFTYAVKN---EYWYQMYIDGLPI-W--------- 143
            |.|:..|.......::|..|...|.|   :...:..|:   .|.:...:|.:|: |
Mouse   107 SPYKFTFNKKETCKLVCTKTYNTEKAEDKQKLDFLKKSMLLNYQHHWIVDNMPVTWCYEVEDSQK 171

  Fly   144 ---------------GKV-------GERDERDGKYYIFTHKKFDIGYN-------GQQIV----- 174
                           |..       .|..||| .:|||.|....|.|:       |.::|
Mouse   172 FCNPGFPIGCYITDKGHAKDACVISSEFHERD-TFYIFNHVDIKIYYHVVETGSMGARLVAAKLE 235

  Fly   175 -------------------DITLTTEGREELKPGSHINFSYEVNWKPSK-VEFKNRFDKYLDPNF 219
                               ||:....|  |:|    |.::|.::::..| :.:.:|:|..|:...
Mouse   236 PKSFKHTHIDKPDCSGPAMDISNKASG--EIK----IAYTYSISFEEEKNIRWASRWDYILESMP 294

  Fly   220 FQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKDEEIDDMERDLGDEYGWKQVHGDV 284
            ..| |.||||.||.::|:||.|:|:||::|||.||.|||::.:..:|.:    :|:|||.||||:
Mouse   295 HTH-IQWFSIMNSLVIVLFLSGMVAMIMLRTLHKDIARYNQMDSTEDAQ----EEFGWKLVHGDI 354

  Fly   285 FRSPPNTLLFSALVGAGYQLISVVFCVIMFAIVGELY-TERGSMLSTAIFVYAATSPINGYFGGS 348
            ||.|...:|.|..:|:|.|::.:.|..:.||.:|.|. ..||::::.|:.::.......||....
Mouse   355 FRPPRKGMLLSVFLGSGTQILIMTFVTLFFACLGFLSPANRGALMTCAVVLWVLLGTPAGYVAAR 419

  Fly   349 LYARLGGRMWIRQMLVSAFTVPVAVCGTAFLINFIAIGYHASRAIPFGTMVAVTCICLFVILPLT 413
            .|...||..|...:|:::|..|..|....|::|.|..|..:|.||||||:||:..:...:.:|||
Mouse   420 FYKSFGGEKWKTNVLLTSFLCPGIVFADFFIMNLILWGEGSSAAIPFGTLVAILALWFCISVPLT 484

  Fly   414 LVGTVVGRNLDGQPDFPCRVNAVPRPIPEKKWYMEPLIIVLLGGVLPFGSIFIEMYFIFTSFWAY 478
            .:|...|...:. .:.|.|.|.:||.|||:.:|.:||..:::||:||||.|||:::||..|.|::
Mouse   485 FIGAYFGFKKNA-IEHPVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFIQLFFILNSIWSH 548

  Fly   479 KIYYVYGFMLLVFSILTVVTVCVTIVCTYFLLNAEDYRWQWTSFMAAGSTSIYVYAYSFYYFFFK 543
            ::||::||:.|||.||.:.....||:..||.|.||||.|||.||:.:|.|::|...|:.:|||.|
Mouse   549 QMYYMFGFLFLVFIILVITCSEATILLCYFHLCAEDYHWQWRSFLTSGFTAVYFLIYAIHYFFSK 613

  Fly   544 TKMFGLFQTAFYFGYMALFSGALGIICGTVGYVGTNLFVRKIYSNVKID 592
            .::.|...|..||||..:......:..||:|:.....||.||||.||:|
Mouse   614 LQITGTASTILYFGYTMIMVLIFFLFTGTIGFFACFWFVTKIYSVVKVD 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF3	NP_647979.1	EMP70	60..530	CDD:281048	171/540 (32%)
Tm9sf2	NP_542123.3	EMP70	74..618	CDD:397233	179/565 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1278
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoDB	1	1.010	-	-		D135708at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830