Protein Alignment TM9SF3 and Tm9sf2

DIOPT Version :10

• Sequence 1: NP_647979.1
• Gene: TM9SF3 / 38635
• FlyBaseID: FBgn0035622
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_001005554.1
• Gene: Tm9sf2 / 306197
• RGDID: 1359230
• Length: 663
• Species: Rattus norvegicus
• Alignment Length: 634
• Identity: 203/634 - (32%)
• Similarity: 318/634 - (50%)
• Gaps: 100/634 - (15%)

  Fly    37 KYND-REEVVLWMN------TVGPYHNRQETYAYFSLPFCSGQKSSISHYHETLSEALQGVELEF 94
            |.|: :.|:.|::|      :|.||.       |.:..||  |.|......|.|.:.|.|..:|.
  Rat    52 KSNECKAEIELFVNRLDSVESVLPYE-------YTAFDFC--QASEGKRPSENLGQVLFGERIEP 107

  Fly    95 SGYEMEFKSDAPKSVICMVTLQEESA---KAFTYAVKN---EYWYQMYIDGLPI-W--------- 143
            |.|:..|..:....::|..|...|.|   :...:..|:   .|.:...:|.:|: |
  Rat   108 SPYKFTFNKEETCKLVCTKTYHTEKAEDKQKLDFLKKSMLLNYQHHWIVDNMPVTWCYEVEDNQK 172

  Fly   144 ---------------GKV-------GERDERDGKYYIFTHKKFDIGYN-------GQQIV----- 174
                           |..       .|..||| .:|||.|....|.|:       |.::|
  Rat   173 FCNPGFPIGCYITDKGHAKDACVISSEFHERD-TFYIFNHVDIKIQYHVVETGSMGARLVAAKLE 236

  Fly   175 -------------------DITLTTEGREELKPGSHINFSYEVNWKPSK-VEFKNRFDKYLDPNF 219
                               ||:....|  |:|    |.::|.::::..| :.:.:|:|..|:...
  Rat   237 PKSFRHTHIDKPDCSGPAMDISNKASG--EIK----IAYTYSISFEEEKNIRWASRWDYILESMP 295

  Fly   220 FQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKDEEIDDMERDLGDEYGWKQVHGDV 284
            ..| |.||||.||.::|:||.|:|:||::|||.||.|||::.:..:|.:    :|:|||.||||:
  Rat   296 HTH-IQWFSIMNSLVIVLFLSGMVAMIMLRTLHKDIARYNQMDSTEDAQ----EEFGWKLVHGDI 355

  Fly   285 FRSPPNTLLFSALVGAGYQLISVVFCVIMFAIVGELY-TERGSMLSTAIFVYAATSPINGYFGGS 348
            ||.|...:|.|..:|:|.|::.:.|..:.||.:|.|. ..||::::.|:.::.......||....
  Rat   356 FRPPRKGMLLSVFLGSGTQILIMTFVTLFFACLGFLSPANRGALMTCAVVLWVLLGTPAGYVAAR 420

  Fly   349 LYARLGGRMWIRQMLVSAFTVPVAVCGTAFLINFIAIGYHASRAIPFGTMVAVTCICLFVILPLT 413
            .|...||..|...:|:::|..|..|....|::|.|..|..:|.||||||:||:..:...:.:|||
  Rat   421 FYKSFGGEKWKTNVLLTSFLCPGIVFADFFIMNLILWGEGSSAAIPFGTLVAILALWFCISVPLT 485

  Fly   414 LVGTVVGRNLDGQPDFPCRVNAVPRPIPEKKWYMEPLIIVLLGGVLPFGSIFIEMYFIFTSFWAY 478
            .:|...|...:. .:.|.|.|.:||.|||:.:|.:||..:::||:||||.|||:::||..|.|::
  Rat   486 FIGAYFGFKKNA-IEHPVRTNQIPRQIPEQSFYTKPLPGIIMGGILPFGCIFIQLFFILNSIWSH 549

  Fly   479 KIYYVYGFMLLVFSILTVVTVCVTIVCTYFLLNAEDYRWQWTSFMAAGSTSIYVYAYSFYYFFFK 543
            ::||::||:.|||.||.:.....||:..||.|.||||.|||.||:.:|.|::|...|:.:|||.|
  Rat   550 QMYYMFGFLFLVFIILVITCSEATILLCYFHLCAEDYHWQWRSFLTSGFTAVYFLVYAIHYFFSK 614

  Fly   544 TKMFGLFQTAFYFGYMALFSGALGIICGTVGYVGTNLFVRKIYSNVKID 592
            .::.|...|..||||..:......:..||:|:.....||.||||.||:|
  Rat   615 LQITGTASTILYFGYTMIMVLIFFLFTGTIGFFACFWFVTKIYSVVKVD 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF3	NP_647979.1	EMP70	60..530	CDD:460774	171/540 (32%)
Tm9sf2	NP_001005554.1	EMP70	75..619	CDD:460774	179/565 (32%)