Protein Alignment TM9SF3 and Y41D4A.4

DIOPT Version :9

• Sequence 1: NP_647979.1
• Gene: TM9SF3 / 38635
• FlyBaseID: FBgn0035622
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_001368302.1
• Gene: Y41D4A.4 / 176983
• WormBaseID: WBGene00021506
• Length: 589
• Species: Caenorhabditis elegans
• Alignment Length: 535
• Identity: 361/535 - (67%)
• Similarity: 429/535 - (80%)
• Gaps: 5/535 - (0%)

  Fly    13 RAICLCLLIASCYVSLSQADEHNHKYNDREEVVLWMNTVGPYHNRQETYAYFSLPFCSGQKSSIS 77
            |.:...||..|..|   :||||:|.|...|||||||||||||.||||||.|||||||.|:|..|.
 Worm     2 RVLISLLLFTSLLV---EADEHDHLYEVDEEVVLWMNTVGPYSNRQETYTYFSLPFCKGEKKEIG 63

  Fly    78 HYHETLSEALQGVELEFSGYEMEFKSDAPKSVICMVTLQEESAKAFTYAVKNEYWYQMYIDGLPI 142
            |||||:.|:|.||||||||.:::|:::..|:|:|...|.|...|...||::|.|:||||:|.:||
 Worm    64 HYHETMGESLLGVELEFSGLDIKFRTNTKKTVVCEKKLTETDYKTLLYAIQNSYYYQMYLDDMPI 128

  Fly   143 WGKVGERDE--RDGKYYIFTHKKFDIGYNGQQIVDITLTTEGREELKPGSHINFSYEVNWKPSKV 205
            ||.|||.|.  ....|.::|||:.|||||.:|:||:.|||:||.:::||:.:.|:|||.|..|:|
 Worm   129 WGMVGEIDNTVNPPAYKLYTHKRLDIGYNDKQVVDVNLTTDGRVDIRPGAELTFTYEVQWSKSEV 193

  Fly   206 EFKNRFDKYLDPNFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKDEEIDDMERD 270
            :|..||||||||:||||||||||||||||||:||||||.|||:||||||||||.|::.:||::.|
 Worm   194 DFTKRFDKYLDPSFFQHRIHWFSIFNSFMMVVFLVGLVWMILVRTLRKDYARYQKEDSLDDLDAD 258

  Fly   271 LGDEYGWKQVHGDVFRSPPNTLLFSALVGAGYQLISVVFCVIMFAIVGELYTERGSMLSTAIFVY 335
            ||||||||||||||||.|...||||:.:||||.:.:|.....:.|||||.||||||:||.|||||
 Worm   259 LGDEYGWKQVHGDVFRPPSMPLLFSSCIGAGYHVFTVAVITTILAIVGEFYTERGSLLSAAIFVY 323

  Fly   336 AATSPINGYFGGSLYARLGGRMWIRQMLVSAFTVPVAVCGTAFLINFIAIGYHASRAIPFGTMVA 400
            ||.||:|||.|||:|||.|||.||:|||:.||.:|..|||.|||||||||.|||||||||..|:|
 Worm   324 AACSPVNGYAGGSMYARFGGRHWIKQMLLGAFLLPSMVCGVAFLINFIAIYYHASRAIPFTIMLA 388

  Fly   401 VTCICLFVILPLTLVGTVVGRNLDGQPDFPCRVNAVPRPIPEKKWYMEPLIIVLLGGVLPFGSIF 465
            |:.|||||||||||||||:|||:.|..|:||||||||||||:|||:::|.:|.|.||||||||||
 Worm   389 VSAICLFVILPLTLVGTVIGRNMAGSADYPCRVNAVPRPIPDKKWFVQPWLITLAGGVLPFGSIF 453

  Fly   466 IEMYFIFTSFWAYKIYYVYGFMLLVFSILTVVTVCVTIVCTYFLLNAEDYRWQWTSFMAAGSTSI 530
            |||||||||||||||||||||||||..||::|||||||||:|||||||||||:||||....||:.
 Worm   454 IEMYFIFTSFWAYKIYYVYGFMLLVTIILSIVTVCVTIVCSYFLLNAEDYRWRWTSFACGASTAF 518

  Fly   531 YVYAYSFYYFFFKTK 545
            |||.||.||||||||
 Worm   519 YVYMYSMYYFFFKTK 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF3	NP_647979.1	EMP70	60..530	CDD:281048	320/471 (68%)
Y41D4A.4	NP_001368302.1	EMP70	47..533	CDD:397233	330/485 (68%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165222
Domainoid	1	1.000	721	1.000	Domainoid score	I41
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10588
Inparanoid	1	1.050	772	1.000	Inparanoid score	I271
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53553
OrthoDB	1	1.010	-	-		D135708at33208
OrthoFinder	1	1.000	-	-		FOG0005862
OrthoInspector	1	1.000	-	-		oto19143
orthoMCL	1	0.900	-	-		OOG6_104089
Panther	1	1.100	-	-	LDO	PTHR10766
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4192
SonicParanoid	1	1.000	-	-		X4863
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.940