Protein Alignment TM9SF3 and tm9sf4

DIOPT Version :10

• Sequence 1: NP_647979.1
• Gene: TM9SF3 / 38635
• FlyBaseID: FBgn0035622
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: XP_031750207.1
• Gene: tm9sf4 / 100379964
• XenbaseID: XB-GENE-993565
• Length: 642
• Species: Xenopus tropicalis
• Alignment Length: 601
• Identity: 209/601 - (34%)
• Similarity: 326/601 - (54%)
• Gaps: 77/601 - (12%)

  Fly    58 QETYAYFSLPFCSGQKSSISHYHETLSEALQGVELEFSGYEMEFKSDAPKSVIC-----MVTLQE 117
            |..|.|:|||||  |.:.|::..|.|.|.|:|..:..:.:.:...||....|:|     ...|..
 Frog    53 QLPYEYYSLPFC--QPTEIAYKSENLGEVLRGDRIVNTPFRVLMNSDKKCEVLCGGPRQSHVLTV 115

  Fly   118 ESAKAFTYAVKNEYWYQMYIDGLPIWGKVG-----ERDER------------------DGKYYIF 159
            |.:|.....::.:|:..:..|.||:..::.     |.:|:                  :.|:|:.
 Frog   116 EQSKLVAERIREDYYVHLIADNLPVATRLDLYLNREEEEKKKEKDVQFEHGYRLGFIDNNKFYLH 180

  Fly   160 THKKFDIGYNGQQI----------------------VDITLTTEG-----------REELKPG-- 189
            .|..|.:.|:.::|                      .|:..|.:|           .:|:.|.
 Frog   181 NHLSFYLYYHPEEIEEKQEPTFRVVRFEVIPQSIRLEDLKGTDQGLCTVPDSSSSAPQEIDPSKE 245

  Fly   190 SHINFSYEVNWKPSKVEFKNRFDKYLDPNFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKD 254
            :.|.|:|.|:|:.|.:::.:|:|.||..:..|  ||||||.||.::|.||.|::|||::||||||
 Frog   246 NKIIFTYSVHWQESDIKWASRWDTYLTMSDVQ--IHWFSIINSVVVVFFLSGILSMIIIRTLRKD 308

  Fly   255 YARYSKDEEIDD-MERDLGDEYGWKQVHGDVFRSPPNTLLFSALVGAGYQLISVVFCVIMFAIVG 318
            .|.|:|:::|:| ||     |.|||.|||||||.|...::.|:|:|:|.||..::..||..|::|
 Frog   309 IANYNKEDDIEDTME-----ESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLG 368

  Fly   319 ELY-TERGSMLSTAIFVYAATSPINGYFGGSLYARLGGRMWIRQMLVSAFTVPVAVCGTAFLINF 382
            .|. :.||::::||.|::.......|:|.|.||..|.|..|.:....:|...|..|....|::|.
 Frog   369 MLSPSSRGALMTTACFLFMFMGVFGGFFAGRLYRTLKGHRWRKGAFCTATLYPGVVFAICFVLNC 433

  Fly   383 IAIGYHASRAIPFGTMVAVTCICLFVILPLTLVGTVVGRNLDGQP-DFPCRVNAVPRPIPEKKWY 446
            ...|.|:|.|:||.||||:.|:...:.|||..:|...|  ...|| |.|.|.|.:||.|||::||
 Frog   434 FIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFG--FRKQPYDNPVRTNQIPRQIPEQRWY 496

  Fly   447 MEPLIIVLLGGVLPFGSIFIEMYFIFTSFWAYKIYYVYGFMLLVFSILTVVTVCVTIVCTYFLLN 511
            |:..:.:|:.|:||||::|||::|||::.|..:.||::||:.|||.||.|....::||..||.|.
 Frog   497 MKRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLC 561

  Fly   512 AEDYRWQWTSFMAAGSTSIYVYAYSFYYFFFKTKMFGLFQTAFYFGYMALFSGALGIICGTVGYV 576
            ||||||.|.:|:.:|.::.||..|:.:||..|..:.....:..||||..|...:..::.||:|:.
 Frog   562 AEDYRWWWRTFLVSGGSAFYVLIYAVFYFVNKLDIVEFIPSLLYFGYTTLMVLSFWLLTGTIGFY 626

  Fly   577 GTNLFVRKIYSNVKID 592
            ...:|:||||:.||||
 Frog   627 AAYMFIRKIYAAVKID 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TM9SF3	NP_647979.1	EMP70	60..530	CDD:460774	185/535 (35%)
tm9sf4	XP_031750207.1	EMP70	55..599	CDD:460774	191/554 (34%)