DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alp9 and alpi.1

DIOPT Version :9

Sequence 1:	NP_001286944.1	Gene:	Alp9 / 38633	FlyBaseID:	FBgn0035620	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	XP_002937387.2	Gene:	alpi.1 / 548375	XenbaseID:	XB-GENE-854726	Length:	529	Species:	Xenopus tropicalis

Alignment Length:	482	Identity:	211/482 - (43%)
Similarity:	292/482 - (60%)	Gaps:	31/482 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 TISGEETQ-EFWHSASKKLIREKLEFVRNTKKAKNIILFLGDGMGLATLAAARSYIG------GE 101
            ||..||:| |||::.....|.|.|:......:|||:|||||||||:.|:.|.|...|      ||
Frog    23 TIPAEESQPEFWNNKMISRINEALKLKPIQHRAKNLILFLGDGMGVPTVTATRILSGQMKRMLGE 87

  Fly   102 ELKLSFEEFPFTGLSKTYSVDKIVPDSACTSTSYLCGVKANYGTIGVNAHVKRGDCAAMANETNH 166
            |.:|:.::||:|.|||||:||:.|||||.|:|:|.|||||||||:||.|.|||.:|:.|  :.|.
Frog    88 ENELAMDKFPYTALSKTYNVDRQVPDSAGTATAYNCGVKANYGTVGVTAAVKRSNCSNM--KGNE 150

  Fly   167 VFSLGKWAMDAGKAAGLVTTTRVTHASPSGVYAHVADREWENNAVLEEACGELSDGLQDIAVQLI 231
            |.|:.|.|..|||:.|:||||||.||||||.|||:.||:|.::|.:  ....::.|.:|||.|||
Frog   151 VESVLKKAKAAGKSVGIVTTTRVQHASPSGTYAHIPDRDWYSDANM--PADAVNFGCKDIAQQLI 213

  Fly   232 HGEVGSKLKVMLGGGKRSF---------YSPEHYDKGRRTDGRNLVEEFEALDAGNTFVKTQKKL 287
            .   ...:.|:||||::..         |..:....|.|.|||||::|:...:.|..:|..:::|
Frog   214 S---NVDIDVILGGGRKYMTPVGTSDPEYPADKKQNGIRKDGRNLIDEWLRKNKGAQYVWNKEQL 275

  Fly   288 LNVNATETGRLLGLFSKSHMHYHLEQLADPDNNEPTLEEMTQKAIEVLETEEQGYFLFVEGGKID 352
            ..:|.:....::|||..:.|.|.|.:....|   |::.|:|:.||.:|:....|::||||||:||
Frog   276 DKINVSTAKHVMGLFEPADMKYELNRNITTD---PSIVELTEIAIRLLQRNPNGFYLFVEGGRID 337

  Fly   353 ISHHETMARIALDETAELSKAVKKAREMTNPEETLIVVTSDHSHTFSVSGYQPRGSDIFGAAKAN 417
            ..||:..|:.||.|.....:|:|.|.::||..:||.|||:||||.|:..||..|||.|||.|...
Frog   338 HGHHDGQAKQALTEGVMFDRAIKIAGQLTNEMDTLTVVTADHSHVFTFGGYTYRGSSIFGLAPKK 402

  Fly   418 GKDGKPYLALSYANGKSFQDYYNTETHERVDPTSLPTIGDFDQLFPAMVPLESETHGGEDVGVFA 482
            ..|.|.|.::.|.||..|.  ...:....||......:|...|   |.|||:|||||||||.:|:
Frog   403 AFDNKSYTSILYGNGPGFN--LTGQGRPNVDSNISEEVGYLQQ---AAVPLDSETHGGEDVAIFS 462

  Fly   483 SGPWAHLFTGVYEQNTIPHMMAFAACV 509
            .||.:|||.||.||..:.|:||:|||:
Frog   463 KGPMSHLFHGVQEQTYVAHVMAYAACL 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alp9	NP_001286944.1	PRK10518	12..496	CDD:236706	203/467 (43%)
Alp9	NP_001286944.1	ALP_like	75..508	CDD:304875	198/447 (44%)
alpi.1	XP_002937387.2	Alk_phosphatase	55..489	CDD:333956	199/448 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H134333
Inparanoid	1	1.050	382	1.000	Inparanoid score	I2005
OMA	1	1.010	-	-		QHG48882
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	1	1.000	-	-		mtm9329
Panther	1	1.100	-	-	O	PTHR11596
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8508
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.110