DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Alp9 and Alp10

DIOPT Version :9

Sequence 1:	NP_001286944.1	Gene:	Alp9 / 38633	FlyBaseID:	FBgn0035620	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_647976.1	Gene:	Alp10 / 38632	FlyBaseID:	FBgn0035619	Length:	524	Species:	Drosophila melanogaster

Alignment Length:	495	Identity:	238/495 - (48%)
Similarity:	329/495 - (66%)	Gaps:	20/495 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 EERMHPHLPTSPRLRTISGEETQEFWHSASKKLIREKLEFVR--NTKKAKNIILFLGDGMGLATL 91
            |...||.|.:|.....:..|....|||..::.::.:||...:  |..:|||:||||||||.:.|:
  Fly    27 EHAQHPRLQSSRDFEALDEELDTRFWHDKAQSILADKLAGHKKLNENRAKNVILFLGDGMSVHTI 91

  Fly    92 AAARSYIGGEELKLSFEEFPFTGLSKTYSVDKIVPDSACTSTSYLCGVKANYGTIGVNAHVKRGD 156
            ||.|:::|....::.||:||:.||||||:|::..||||.|:|:||.|||||||||||||.|:|||
  Fly    92 AATRAFMGDSNKQVFFEKFPYLGLSKTYAVNERTPDSANTATAYLTGVKANYGTIGVNAQVQRGD 156

  Fly   157 CAAMANETNHVFSLGKWAMDAGKAAGLVTTTRVTHASPSGVYAHVADREWENNA-VLEEACGELS 220
            |  :.|.::||.|:|:||.:|||.||||||.|||||||:||||||::|.||::. ::...|.  .
  Fly   157 C--VTNSSSHVQSIGQWAQEAGKWAGLVTTARVTHASPAGVYAHVSERNWEHDGEIISSKCS--P 217

  Fly   221 DGLQDIAVQLIHGEVGSKLKVMLGGGKRSFYSPEHYDK----GRRTDGRNLVEEFEAL----DAG 277
            |...|||.||:...||.:|:|::|||:..|.....:|:    |.|||||:|:.::..:    .|.
  Fly   218 DVNTDIARQLVEWPVGQELRVIMGGGRSYFRDQSQHDETGVSGLRTDGRDLISDWREIKKQQGAE 282

  Fly   278 NTFVKTQKKLLNVNATETGRLLGLFSKSHMHYHLE-QLADPDNNEPTLEEMTQKAIEVLETEEQG 341
            ..:|.:.|.|...:.::|..|||||..||:.||.: :....::.||:|.:||:.||::|...|:|
  Fly   283 GKYVWSLKGLKETDISKTDYLLGLFDTSHLPYHGDRRRTHYEDAEPSLSDMTEAAIKMLSKNEEG 347

  Fly   342 YFLFVEGGKIDISHHETMARIALDETAELSKAVKKAREMTNPEETLIVVTSDHSHTFSVSGYQPR 406
            ||||||.|:||::||.|.|..||::|.|.:.||:.||:||:.|:||||||||||||.|::||..|
  Fly   348 YFLFVESGRIDMAHHATKAMKALEDTEEFAAAVELARKMTDEEDTLIVVTSDHSHTMSINGYPYR 412

  Fly   407 GSDIFGAAKANGKDGKPYLALSYANGKSFQDYYNTETHERVDPTSLPTI-GDFDQLFPAMVPLES 470
            ..:|...|.....|..|:..||||||..|.|.|:|: ..|:|.:...|. .:|:  |.|.|||.|
  Fly   413 RQNILSLAPNLADDELPFTILSYANGPGFDDTYSTK-DGRIDLSHADTTSAEFE--FQATVPLSS 474

  Fly   471 ETHGGEDVGVFASGPWAHLFTGVYEQNTIPHMMAFAACVG 510
            ||||.||||||||||:.|||||.|||:.||.|||:||.:|
  Fly   475 ETHGAEDVGVFASGPFEHLFTGNYEQSAIPAMMAYAANIG 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alp9	NP_001286944.1	PRK10518	12..496	CDD:236706	228/479 (48%)
Alp9	NP_001286944.1	ALP_like	75..508	CDD:304875	224/443 (51%)
Alp10	NP_647976.1	PhoA	56..510	CDD:224699	226/460 (49%)
Alp10	NP_647976.1	ALP_like	75..511	CDD:304875	223/442 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466622
Domainoid	1	1.000	363	1.000	Domainoid score	I896
eggNOG	1	0.900	-	-		E1_COG1785
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	383	1.000	Inparanoid score	I2001
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	1	1.000	-	-		mtm6481
orthoMCL	1	0.900	-	-		OOG6_100381
Panther	1	1.100	-	-	P	PTHR11596
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X159
	11	10.800