Protein Alignment Alp9 and Alppl2

DIOPT Version :10

• Sequence 1: NP_647977.1
• Gene: Alp9 / 38633
• FlyBaseID: FBgn0035620
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_031459.3
• Gene: Alppl2 / 11650
• MGIID: 108009
• Length: 529
• Species: Mus musculus
• Alignment Length: 532
• Identity: 206/532 - (38%)
• Similarity: 297/532 - (55%)
• Gaps: 71/532 - (13%)

  Fly    16 VWGAAV----------PGRAPVDEERMHPHLPTSPRLRTISGEETQEFWHSASKKLI--REKLEF 68
            :|||.:          |...||:                   ||...||:..:.:.:  .:||:.
Mouse     1 MWGACLLLLGLSLQVCPSVIPVE-------------------EENPAFWNRKAAEALDAAKKLKP 46

  Fly    69 VRNTKKAKNIILFLGDGMGLATLAAARSYIG------GEELKLSFEEFPFTGLSKTYSVDKIVPD 127
            ::.:  |||:::.:|||||::|:.|.|...|      |.|.:|:.:.||...|||||:.||.:||
Mouse    47 IQTS--AKNLVILMGDGMGVSTVTATRILKGQQQGHLGPETQLAMDRFPHMALSKTYNTDKQIPD 109

  Fly   128 SACTSTSYLCGVKANYGTIGVNAHVKRGDCAAMANET--NHVFSLGKWAMDAGKAAGLVTTTRVT 190
            ||.|.|::|||||.|...||::|..:...|    |.|  |.|.|:...|..|||:.|:||||.|.
Mouse   110 SAGTGTAFLCGVKTNMKVIGLSAAARFNQC----NTTWGNEVVSVMHRAKKAGKSVGVVTTTSVQ 170

  Fly   191 HASPSGVYAHVADREWENNAVLEEACGELSDGLQDIAVQLIHGEVGSKLKVMLGGGKRSF----- 250
            ||||:|.|||..:|.|.::|.:..:.  |.||.:||:.|||.   ...:.|:||||::..
Mouse   171 HASPAGTYAHTVNRGWYSDAQMPASA--LQDGCKDISTQLIS---NMDIDVILGGGRKFMFPKGT 230

  Fly   251 ----YSPEHYDKGRRTDGRNLVEEFEALDAGNTFVKTQKKLL--NVNATETGRLLGLFSKSHMHY 309
                |..:....|.|.||||||:|:.|...|..:|..:.:|:  ::|.:.| .|:|||..:.|.|
Mouse   231 PDQEYPTDTKQAGTRLDGRNLVQEWLAKHQGARYVWNRSELIQASLNRSVT-HLMGLFEPNDMKY 294

  Fly   310 HLEQLADPDNNEPTLEEMTQKAIEVLETEEQGYFLFVEGGKIDISHHETMARIALDETAELSKAV 374
            .:.:  || ..:|:|.|||:.|:.:|....:|::||||||:||..||||:|..||.|......||
Mouse   295 EIHR--DP-AQDPSLAEMTEVAVRMLSRNPKGFYLFVEGGRIDHGHHETVAYRALTEAVMFDSAV 356

  Fly   375 KKAREMTNPEETLIVVTSDHSHTFSVSGYQPRGSDIFGAAKANGKDGKPYLALSYANGKSFQDYY 439
            .||.::|:.::|:|:||:||||.||..||..||:.|||.|....:|||.:.::.|.||..::.:.
Mouse   357 DKADKLTSEQDTMILVTADHSHVFSFGGYTQRGASIFGLAPFKAEDGKSFTSILYGNGPGYKLHN 421

  Fly   440 NTETHERVDPTSLPTIGDFDQLFPAMVPLESETHGGEDVGVFASGPWAHLFTGVYEQNTIPHMMA 504
            ........:.:|.||   :.|  .|.|||.||||.||||.:||.||.|||..||.|||.|.|:||
Mouse   422 GARADVTEEESSNPT---YQQ--QAAVPLSSETHSGEDVAIFARGPQAHLVHGVQEQNYIAHVMA 481

  Fly   505 FAACVGDGLTAC 516
            ||||: :..|.|
Mouse   482 FAACL-EPYTDC 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp9	NP_647977.1	ALP_like	75..508	CDD:474031	190/451 (42%)
Alppl2	NP_031459.3	Alk_phosphatase	51..486	CDD:395188	191/452 (42%)