DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Alp9 and alpi.2

DIOPT Version :9

Sequence 1:	NP_001286944.1	Gene:	Alp9 / 38633	FlyBaseID:	FBgn0035620	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001116946.1	Gene:	alpi.2 / 100144722	XenbaseID:	XB-GENE-854953	Length:	532	Species:	Xenopus tropicalis

Alignment Length:	500	Identity:	214/500 - (42%)
Similarity:	296/500 - (59%)	Gaps:	33/500 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 MHPHLPTSPRLRTISGEETQEFWHSASKKLIREKLEFVRNTKKAKNIILFLGDGMGLATLAAARS 96
            :||  .|...:.::..|:..:||:..:|:.::..|.....|.:|||:|:|||||||:.|:||||.
Frog    25 VHP--STGVVVSSLEAEKNPKFWNDQAKETLKNALNLNPITHRAKNLIMFLGDGMGVTTIAAARI 87

  Fly    97 YIG------GEELKLSFEEFPFTGLSKTYSVDKIVPDSACTSTSYLCGVKANYGTIGVNAHVKRG 155
            |.|      |||..::.|:||:..|||.|:||..|||||.|.|:||||||||.||:||:|....|
Frog    88 YQGQVEGQPGEENIMAMEKFPYVALSKVYNVDAQVPDSAGTGTAYLCGVKANSGTLGVSAAAIYG 152

  Fly   156 DCAAMANETNHVFSLGKWAMDAGKAAGLVTTTRVTHASPSGVYAHVADREWENNAVLEEACGELS 220
            :|  ::::.|.|.|:...|..|||:.|:||||||.||||...|||.|.|.|.::..:..|.  ::
Frog   153 NC--VSSKGNEVTSILHRAKLAGKSVGIVTTTRVQHASPGAAYAHSASRNWYSDNEMTSAM--IN 213

  Fly   221 DGLQDIAVQLIHGEVGSKLKVMLGGGKRSFY-----SPEH----YDKGRRTDGRNLVEEFEALDA 276
            :|.:|||.||:|   .:.:.|:||||:...|     .||:    .|:|.|.||.||.:.:.:...
Frog   214 NGCKDIAYQLVH---NTDIDVILGGGRAYMYPAGTPDPEYPGSSADRGLRRDGLNLTDIWLSKRQ 275

  Fly   277 GNTFVKTQKKLLNVNATETGRLLGLFSKSHMHYHLEQLADPDNNEPTLEEMTQKAIEVLETEEQG 341
            ...:|..:::...||...|..|:|||....|.|.|.:.|..|   |:|.|||:|||.:|....:|
Frog   276 NARYVWNKEQFNAVNVDTTDYLMGLFEPKDMKYELNRNASLD---PSLAEMTEKAIRILSKNPKG 337

  Fly   342 YFLFVEGGKIDISHHETMARIALDETAELSKAVKKAREMTNPEETLIVVTSDHSHTFSVSGYQPR 406
            :|||||||:||..||:..|:.:|.|..|..|||.:..::|...|||.|||:||||.|:..||..|
Frog   338 FFLFVEGGRIDHGHHDGNAKQSLTEALEFDKAVLRGGQLTQENETLTVVTADHSHVFTFGGYTDR 402

  Fly   407 GSDIFGAAKANGKDGKPYLALSYANGKSFQDYYNTETHERVDPTSLPTIGDFDQLFPAMVPLESE 471
            |:.|||.|.:...|.|||.:|.|.||..    |......|.:.|.:.| |....|..|.||:.||
Frog   403 GNSIFGLAPSLASDRKPYTSLLYGNGPG----YPLPDAIRANITGVNT-GSNSYLQQAAVPVVSE 462

  Fly   472 THGGEDVGVFASGPWAHLFTGVYEQNTIPHMMAFAACVGDGLTAC 516
            |||||||.:.|.||.||||.|.:||:.|.|:||:|||: :..|.|
Frog   463 THGGEDVAIMAKGPQAHLFHGFHEQSYIAHVMAYAACL-EPYTEC 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alp9	NP_001286944.1	PRK10518	12..496	CDD:236706	203/478 (42%)
Alp9	NP_001286944.1	ALP_like	75..508	CDD:304875	201/447 (45%)
alpi.2	NP_001116946.1	Alk_phosphatase	66..500	CDD:333956	202/448 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	382	1.000	Inparanoid score	I2005
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	1	1.000	-	-		mtm9329
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.060