DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Alp10 and Alp13

DIOPT Version :9

Sequence 1:	NP_647976.1	Gene:	Alp10 / 38632	FlyBaseID:	FBgn0035619	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_649978.2	Gene:	Alp13 / 41236	FlyBaseID:	FBgn0037786	Length:	479	Species:	Drosophila melanogaster

Alignment Length:	485	Identity:	129/485 - (26%)
Similarity:	205/485 - (42%)	Gaps:	110/485 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SCLILCFFALLVI--QARSDLADDQEHAQHPRLQSSRDFEALDEELDTRFWHDK---AQSILADK 63
            :|||.....||.|  ..|.::.:|..:.                 .|..:|.||   :|.|..||
  Fly    27 TCLITVMVTLLCIGFMTRYEVENDVANV-----------------ADVDYWKDKVATSQKIWYDK 74

  Fly    64 LAGHKKLNE-------NRAKNVILFLGDGMSVHTIAATRAFMGDS---NKQVFFEKFPYLGLSKT 118
              |..:|||       ...|||.:|:..|:.....||.|....|:   |....:::||:|...|.
  Fly    75 --GIDELNEALRPQDLTYPKNVRIFVIQGIDGRDWAAFRFPTSDASRGNTNFIWDRFPHLARLKN 137

  Fly   119 YAVNERTPDSANTATAYLTGVKANYGTIGVNAQVQRGDC--VTNSSSHVQSIGQWAQEAGKWAGL 181
            ....:.....|:.:.|...|:..:  .:..|.|    ||  :.|::....||.:.||.||...|.
  Fly   138 SCSQQFPCQVASVSRALWLGIPLD--KVPDNQQ----DCGRLFNATQGPISILRQAQLAGLRTGF 196

  Fly   182 VTTARVTHASPAGVYAHVSERNWEHDGEI----ISSKCSPDVNTDIARQLVEWPVGQELRVIMGG 242
            |||.|:|  .|.|.....:..|:|.|..:    |.|.|.     |||:||:....|:.|.|::||
  Fly   197 VTTQRIT--GPTGAALGNANGNFECDESMPLNSIKSGCQ-----DIAQQLISDETGKFLNVLIGG 254

  Fly   243 GR---SYFRDQSQHDETGVSGLRT-DGRDLISDWREIKKQQGAEGKYVWSL----KGLKETDISK 299
            ||   |.....:::|........: |||:|:.|||..|.::....:.::.|    ..|:..:.|.
  Fly   255 GRQMLSSLVPNTKYDPVDEMLCESNDGRNLLKDWRNQKLKESKINRIIFDLIQRRDELESLNSSS 319

  Fly   300 TDYLLGLFDTSHLPYHGDRRRTHYEDAEPSLSDMTEAAIKMLSKNEEGYFLFVE----SGRIDMA 360
            .|||:|:.....|  .|:.:       .|||..|.:.::.:|:|.::||.|.||    || ||
  Fly   320 FDYLMGVMANGDL--SGNSK-------APSLKLMVDKSLNVLTKYKQGYLLIVEQFIPSG-ID-- 372

  Fly   361 HHATKAMKALEDTEEFAAAVELARKMTDEEDTLIVVTSDHSHTMSINGYPYRRQNI------LSL 419
              ..:.::.|.||     .|.|.:    ::|||.:|..    |.:|  ||....::      :||
  Fly   373 --KREQLQLLNDT-----LVNLHK----DQDTLTLVLM----TNAI--YPKPSLDVSEETETISL 420

  Fly   420 APNLADD----------ELPFTILSYANGP 439
            .|.:.::          ::|...|.:|.||
  Fly   421 LPEIFNEAESEIQKRLHQMPSESLLFAQGP 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alp10	NP_647976.1	PhoA	56..510	CDD:224699	117/428 (27%)
Alp10	NP_647976.1	ALP_like	75..511	CDD:304875	109/402 (27%)
Alp13	NP_649978.2	ALP_like	127..472	CDD:304875	99/366 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466688
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1785
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11596
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850