Protein Alignment Alp10 and Alpi

DIOPT Version :10

• Sequence 1: NP_647976.1
• Gene: Alp10 / 38632
• FlyBaseID: FBgn0035619
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_073156.3
• Gene: Alpi / 24197
• RGDID: 2099
• Length: 540
• Species: Rattus norvegicus
• Alignment Length: 488
• Identity: 204/488 - (41%)
• Similarity: 288/488 - (59%)
• Gaps: 37/488 - (7%)

  Fly    45 EELDTRFWHDKAQSILADKLAGHKKLN--ENRAKNVILFLGDGMSVHTIAATRAFMGD------S 101
            ||.:..||:.||:    :.|...|||.  :..|||:||||||||.|.|:.|||...|.      .
  Rat    25 EEENPVFWNQKAK----EALDVAKKLQPIQTSAKNLILFLGDGMGVPTVTATRILKGQLGGHLGP 85

  Fly   102 NKQVFFEKFPYLGLSKTYAVNERTPDSANTATAYLTGVKANYGTIGVNAQVQRGDCVTNSSSHVQ 166
            ...:..:.||:..|||||.|:.:.||||.||||||.||||||.||||:|..:...|.:...:.|.
  Rat    86 ETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGVSAAARFNQCNSTFGNEVF 150

  Fly   167 SIGQWAQEAGKWAGLVTTARVTHASPAGVYAHVSERNWEHDGEIISSKCSPDVNTDIARQLVEWP 231
            |:...|::|||..|:|||.||.||||||.|||...|:|..|.::.||....... |||.||:.
  Rat   151 SVMHRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRDWYSDADMPSSALQEGCK-DIATQLIS-- 212

  Fly   232 VGQELRVIMGGGRSYFRDQSQHD-----ETGVSGLRTDGRDLISDWREIKKQQGAEGKYVWSLKG 291
             ..::.||:||||.:...:...|     ::..||:|.|.|:|:.:|  :.|.||.  :|||:.:.
  Rat   213 -NMDIDVILGGGRKFMFPKGTPDPEYPGDSDQSGVRLDSRNLVEEW--LAKYQGT--RYVWNREQ 272

  Fly   292 LKET--DISKTDYLLGLFDTSHLPYHGDRRRTHYEDAEPSLSDMTEAAIKMLSKNEEGYFLFVES 354
            |.:.  |.:.| .|:|||:.:.:.|..:|..:    |:|||::|||.|:::||:|.:|::||||.
  Rat   273 LMQASQDPAVT-RLMGLFEPAEMKYDVNRNAS----ADPSLAEMTEVAVRLLSRNPQGFYLFVEG 332

  Fly   355 GRIDMAHHATKAMKALEDTEEFAAAVELARKMTDEEDTLIVVTSDHSHTMSINGYPYRRQNILSL 419
            ||||..|||..|..||.:...|.:|:|.|.::|:|:|||.::|:||||..:..||..|..:|..|
  Rat   333 GRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGL 397

  Fly   420 APNLADDELPFTILSYANGPGFDDTYSTKDG-RIDLSHADTTSAEFEFQATVPLSSETHGAEDVG 483
            ||..|.|...:|.:.|.||||    |....| |.:::.|::....::.||.|||||||||.|||.
  Rat   398 APLNAQDGKSYTSILYGNGPG----YVLNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVA 458

  Fly   484 VFASGPFEHLFTGNYEQSAIPAMMAYAANIGPF 516
            :||.||..||..|..||:.|..:||:|..:.|:
  Rat   459 IFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPY 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp10	NP_647976.1	ALP_like	76..514	CDD:474031	192/451 (43%)
Alpi	NP_073156.3	Alk_phosphatase	53..488	CDD:395188	193/451 (43%)