Protein Alignment Alp10 and Alppl2

DIOPT Version :9

• Sequence 1: NP_647976.1
• Gene: Alp10 / 38632
• FlyBaseID: FBgn0035619
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_031459.3
• Gene: Alppl2 / 11650
• MGIID: 108009
• Length: 529
• Species: Mus musculus
• Alignment Length: 488
• Identity: 200/488 - (40%)
• Similarity: 290/488 - (59%)
• Gaps: 37/488 - (7%)

  Fly    45 EELDTRFWHDKAQSILADKLAGHKKLN--ENRAKNVILFLGDGMSVHTIAATRAFMGDS------ 101
            ||.:..||:.||    |:.|...|||.  :..|||:::.:||||.|.|:.|||...|..
Mouse    23 EEENPAFWNRKA----AEALDAAKKLKPIQTSAKNLVILMGDGMGVSTVTATRILKGQQQGHLGP 83

  Fly   102 NKQVFFEKFPYLGLSKTYAVNERTPDSANTATAYLTGVKANYGTIGVNAQVQRGDCVTNSSSHVQ 166
            ..|:..::||::.|||||..:::.||||.|.||:|.|||.|...||::|..:...|.|...:.|.
Mouse    84 ETQLAMDRFPHMALSKTYNTDKQIPDSAGTGTAFLCGVKTNMKVIGLSAAARFNQCNTTWGNEVV 148

  Fly   167 SIGQWAQEAGKWAGLVTTARVTHASPAGVYAHVSERNWEHDGEIISSKCSPDVNTDIARQLVEWP 231
            |:...|::|||..|:|||..|.||||||.|||...|.|..|.::.:|... |...||:.||:.
Mouse   149 SVMHRAKKAGKSVGVVTTTSVQHASPAGTYAHTVNRGWYSDAQMPASALQ-DGCKDISTQLIS-- 210

  Fly   232 VGQELRVIMGGGRSYF-----RDQSQHDETGVSGLRTDGRDLISDWREIKKQQGAEGKYVWSLKG 291
             ..::.||:||||.:.     .||....:|..:|.|.|||:|:.:|  :.|.|||  :|||:...
Mouse   211 -NMDIDVILGGGRKFMFPKGTPDQEYPTDTKQAGTRLDGRNLVQEW--LAKHQGA--RYVWNRSE 270

  Fly   292 LKETDISKT-DYLLGLFDTSHLPYHGDRRRTHYEDA-EPSLSDMTEAAIKMLSKNEEGYFLFVES 354
            |.:..:::: .:|:|||:.:.:.|     ..|.:.| :|||::|||.|::|||:|.:|::||||.
Mouse   271 LIQASLNRSVTHLMGLFEPNDMKY-----EIHRDPAQDPSLAEMTEVAVRMLSRNPKGFYLFVEG 330

  Fly   355 GRIDMAHHATKAMKALEDTEEFAAAVELARKMTDEEDTLIVVTSDHSHTMSINGYPYRRQNILSL 419
            ||||..||.|.|.:||.:...|.:||:.|.|:|.|:||:|:||:||||..|..||..|..:|..|
Mouse   331 GRIDHGHHETVAYRALTEAVMFDSAVDKADKLTSEQDTMILVTADHSHVFSFGGYTQRGASIFGL 395

  Fly   420 APNLADDELPFTILSYANGPGFDDTYSTKDG-RIDLSHADTTSAEFEFQATVPLSSETHGAEDVG 483
            ||..|:|...||.:.|.||||    |...:| |.|::..::::..::.||.||||||||..|||.
Mouse   396 APFKAEDGKSFTSILYGNGPG----YKLHNGARADVTEEESSNPTYQQQAAVPLSSETHSGEDVA 456

  Fly   484 VFASGPFEHLFTGNYEQSAIPAMMAYAANIGPF 516
            :||.||..||..|..||:.|..:||:||.:.|:
Mouse   457 IFARGPQAHLVHGVQEQNYIAHVMAFAACLEPY 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp10	NP_647976.1	PhoA	56..510	CDD:224699	192/469 (41%)
		ALP_like	75..511	CDD:304875	186/449 (41%)
Alppl2	NP_031459.3	Alk_phosphatase	51..486	CDD:333956	188/451 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847856
Domainoid	1	1.000	373	1.000	Domainoid score	I882
eggNOG	1	0.900	-	-		E1_COG1785
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	386	1.000	Inparanoid score	I2003
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48882
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	1	1.000	-	-		mtm8682
orthoMCL	1	0.900	-	-		OOG6_100381
Panther	1	1.100	-	-	O	PTHR11596
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.800