DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment spo and CYP71B23

DIOPT Version :9

Sequence 1:	NP_001286943.1	Gene:	spo / 38631	FlyBaseID:	FBgn0003486	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_189252.1	Gene:	CYP71B23 / 822222	AraportID:	AT3G26210	Length:	501	Species:	Arabidopsis thaliana

Alignment Length:	565	Identity:	126/565 - (22%)
Similarity:	216/565 - (38%)	Gaps:	142/565 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ALIYTILAILLSVLATSYICIIYGVKRRVLQPVKTKNSTEINHNAYQKYTQAPGPRPWPIIGNLH 68
            ::....|.:||.:|.|    ||:           |:.|..      .|....|||...|||||||
plant     2 SIFLCFLLLLLLLLVT----IIF-----------TRKSQS------SKLKLPPGPPKLPIIGNLH 45

  Fly    69 LLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSGRPD-----FI 128
            .|:   ..|......|.:.:|.:..|..|:...:|:::.:...|||..:......||:     .|
plant    46 YLN---GLPHKCLLNLWKIHGPVMQLQLGYVPLVVISSNQAAEEVLKTHDLDCCSRPETIASKTI 107

  Fly   129 RYH-KLFG----GERSNSLALCDWSQLQQKRRNLARRHC-SPREFSCF-YMKMSQIGCEEMEHWN 186
            .|: |..|    ||        :|..|    |.||.... |.::|:.| |::.     ||.:...
plant   108 SYNFKDIGFAPYGE--------EWRAL----RKLAVIELFSLKKFNSFRYIRE-----EENDLLV 155

  Fly   187 RELGNQLVPGEPINIKPLILKACANMFSQYMCSLRFD--------YDDVDFQQIVQYFDEI---F 240
            ::|........|:|:|    ||...:.:..:|.|.|.        .|:...:.:....::|   |
plant   156 KKLSEASEKQSPVNLK----KALFTLSASIVCRLAFGQNLHESEFIDEDSMEDLASRSEKIQAKF 216

  Fly   241 WEINQGHPLDFLP--WLYPFYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDRDFTDALL 303
            ...|      |.|  |:       |:||...|.::           .|:..|||.......|..|
plant   217 AFSN------FFPGGWI-------LDKITGQSKSL-----------NEIFADLDGFFNQVLDDHL 257

  Fly   304 K---SLLEDKDVSRNTIIFML---------------------EDFIGGHSAVGNLVMLVLAYIAK 344
            |   .:||..||. :.:|.|:                     :.|:.|.:.....::..:..:.:
plant   258 KPGRKVLETPDVV-DVMIDMMNKQSQDGSFKLTTDHIKGIISDIFLAGVNTSATTILWAMTELIR 321

  Fly   345 NVDIGRRIQEEIDAIIEEENRSINLLDMNAMPYTMATIFEVLR-YSSSP-IVPHVATEDTVISGY 407
            |..:.:::|:|:..::.|:...|...|:|.:.|....|.|..| :.::| ::|..|.....|.||
plant   322 NPRVMKKVQDEVRTVLGEKRDRITEQDLNQLNYFKLVIKETFRLHPAAPLLLPREAMAKIKIQGY 386

  Fly   408 GVTKGTIVFINNYVLNTSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNI 472
            .:.:.|.:.:|.|.:......|.||:||.|.||:              ||.::......:|
plant   387 DIPEKTQIMVNVYAIGRDPDLWENPEEFKPERFV--------------DSSVDYRGLNFEL---- 433

  Fly   473 PHFLPFSIGKRTCIGQNLVRGFGFLVVVNVMQRYNISSHNPSTIK 517
               |||..|:|.|.|..:......|.::|::..::.......|:|
plant   434 ---LPFGSGRRICPGMTMGIATVELGLLNLLYFFDWGLPEGRTVK 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_001286943.1	p450	56..540	CDD:299894	116/513 (23%)
CYP71B23	NP_189252.1	CYP71-like	62..493	CDD:410695	103/481 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000