DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment spo and CYP78A6

DIOPT Version :9

Sequence 1:	NP_001286943.1	Gene:	spo / 38631	FlyBaseID:	FBgn0003486	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_182189.1	Gene:	CYP78A6 / 819278	AraportID:	AT2G46660	Length:	530	Species:	Arabidopsis thaliana

Alignment Length:	533	Identity:	131/533 - (24%)
Similarity:	232/533 - (43%)	Gaps:	109/533 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LIYTILAILLSVLATSYIC-----------IIYGVKRRVLQPVKTKNSTEINHNAYQKYTQAPGP 58
            |.:::||:.:..||.|...           .::|  |.:....||.|             ..|||
plant    25 LAFSLLAVTIIWLAISLFLWTYPGGPAWGKYLFG--RLISGSYKTGN-------------VIPGP 74

  Fly    59 RPWPIIGNLHLLD------RYRDSPFAGFTALAQQYG--DIYSLTFGHTRCLVVNNLELIREVLN 115
            :.:|::|::.|:.      |..|:        |:::|  .:.:.:.|.||.:|..|.::.:|:|
plant    75 KGFPLVGSMSLMSSTLAHRRIADA--------AEKFGAKRLMAFSLGETRVIVTCNPDVAKEIL- 130

  Fly   116 QNGKVMSGRPDFIR---YHKLFGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYMKMSQ- 176
             |..|.:.||  ::   |..:|    :.::.........:..|.:|..|.    ||...::.::
plant   131 -NSPVFADRP--VKESAYSLMF----NRAIGFAPHGVYWRTLRRIASNHL----FSTKQIRRAET 184

  Fly   177 ----IGCEEMEHWNRELGNQLVPGEPINIKPLILKACANMFSQYMCSL-----RFDYDDVDFQQI 232
                |..:.:|...::..|     ||..::.|:..|..|   ..|||:     ..:.:.|:.:::
plant   185 QRRVISSQMVEFLEKQSSN-----EPCFVRELLKTASLN---NMMCSVFGQEYELEKNHVELREM 241

  Fly   233 VQYFDEIFWEINQGHPLDFLPWLYPF-YQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDR 296
            |:...::...:|.   .|.||||..| .||..::.......:..|:...|..||..:.||   .|
plant   242 VEEGYDLLGTLNW---TDHLPWLSEFDPQRLRSRCSTLVPKVNRFVSRIISEHRNQTGDL---PR 300

  Fly   297 DFTDALLKSLLEDKDVSRNTIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEEIDAIIE 361
            ||.|.||.....||....:.|..:.|....|...|..|:..:||.:..:.|:...:|.|:|.::
plant   301 DFVDVLLSLHGSDKLSDPDIIAVLWEMIFRGTDTVAVLIEWILARMVLHPDMQSTVQNELDQVV- 364

  Fly   362 EENRSINLLDMNAMPYTMATIFEVLR-YSSSPIV--PHVATEDTVISGYGVTKGTIVFINNYVLN 423
            .::|:::..|:.::||..|.:.|||| :...|::  ..:|..||::.|..|..||...:|.:.::
plant   365 GKSRALDESDLASLPYLTAVVKEVLRLHPPGPLLSWARLAITDTIVDGRLVPAGTTAMVNMWAVS 429

  Fly   424 TSEKFWVNPKEFNPLRFLEPSKEQSPKNS-KGSDSGIESDNEKLQLKRNIPHFLPFSIGKRTCIG 487
            .....||:|.||.|.||:  :||...:.| .|||         |:|       .||..|:|.|.|
plant   430 HDPHVWVDPLEFKPERFV--AKEGEVEFSVLGSD---------LRL-------APFGSGRRICPG 476

  Fly   488 QNLVRGFGFLVVV 500
            :||    ||..|:
plant   477 KNL----GFTTVM 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_001286943.1	p450	56..540	CDD:299894	120/471 (25%)
CYP78A6	NP_182189.1	p450	25..523	CDD:386267	131/533 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000