DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment spo and si:dkey-286h2.3

DIOPT Version :9

Sequence 1:	NP_001286943.1	Gene:	spo / 38631	FlyBaseID:	FBgn0003486	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_001073322.1	Gene:	si:dkey-286h2.3 / 790965	ZFINID:	ZDB-GENE-161014-2	Length:	496	Species:	Danio rerio

Alignment Length:	571	Identity:	151/571 - (26%)
Similarity:	239/571 - (41%)	Gaps:	114/571 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLAALIYTILAILLSVLATSYICIIYGVKRRVLQPVKTKNSTEINHNAYQKYTQAPGPRPWPIIG 65
            ||.||:...|...|..|           :.|:.:|   :|.             .|||.|.||.|
Zfish     1 MLTALVLLCLGAFLLYL-----------QLRIRRP---RNF-------------PPGPAPVPIFG 38

  Fly    66 NLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSGRPDFIRY 130
            ||..|:..  :|.......||.||.||.:..|....:|:...::|:|.|...|...:||.:.:..
Zfish    39 NLLQLNHI--NPIKDLDKFAQHYGSIYGIYIGSKPAVVLTGQKMIKEALITQGAEFAGRSNKMMV 101

  Fly   131 HKLFGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEMEHWNRELGNQLVP 195
            ..:   .||..:.:.|:.:..::.|..|.  .:.|.|......|.|...||::|....|...  .
Zfish   102 SHV---TRSKGVIMADYGESWREHRRFAL--TTLRNFGLGKKSMEQRILEEVKHICLLLEES--A 159

  Fly   196 GEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQYFDEIFWEINQGHPLDFLPW--LY-- 256
            |:||:.:.|..:|.:|:.:..:...||||.|..||.::...::: .:|..|      ||  ||
Zfish   160 GKPIDPQHLYHQAASNIIASIIFRSRFDYQDEYFQTLITTMEKL-TKIAIG------PWAMLYEI 217

  Fly   257 ---------PFYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDRDFTDALLKSL--LEDK 310
                     ||:     |...:...|...:::.:..|:...| ..|| ||..|..|:.:  ..||
Zfish   218 APVLRIFPLPFH-----KAFQYFEQITNHVLKVVEEHKTSRV-AGEP-RDLIDCYLEEMNRRSDK 275

  Fly   311 DVSRN-----TIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEEIDAIIEEENRSINLL 370
            ..:.:     |::|.|  ||.|.....|.:..:..|:.....|..:.|.|||.::...:. :...
Zfish   276 HTTFDESQMVTLLFDL--FIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDH-VTYE 337

  Fly   371 DMNAMPYTMATIFEVLRYSSSPIVP----HVATEDTVISGYGVTKGTIVFINNYVLNT--SEKFW 429
            |.|||.:..|.|.|..|.:.  |||    |.|..||.:.||.:.||||:.  .|:.::  .|..|
Zfish   338 DRNAMHFVQAVIHEGQRVAD--IVPLSMFHTARTDTQLRGYSIPKGTIII--PYLSSSLREEGQW 398

  Fly   430 VNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIGKRTCIGQNLVRGF 494
            ..|.||||..||                     |||.:..:| ..|:|||.|.|.|:|:||.|..
Zfish   399 KFPHEFNPQNFL---------------------NEKGEFVKN-DAFMPFSAGPRVCLGENLARME 441

  Fly   495 GFLVVVNVMQRYNI----SSHNPSTIKISPESLALPADCFPLVL---TPRE 538
            .||::|.|::::.:    .:..|....|...:.:|..  :|:::   ||.|
Zfish   442 LFLILVTVLRKFRLVWPKDAEEPDFTYIYGGTQSLKP--YPMIVKLRTPGE 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_001286943.1	p450	56..540	CDD:299894	141/516 (27%)
si:dkey-286h2.3	NP_001073322.1	p450	28..485	CDD:278495	138/510 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000