Protein Alignment spo and Cyp2d26

DIOPT Version :10

• Sequence 1: NP_647975.2
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_083838.1
• Gene: Cyp2d26 / 76279
• MGIID: 1923529
• Length: 500
• Species: Mus musculus
• Alignment Length: 574
• Identity: 149/574 - (25%)
• Similarity: 240/574 - (41%)
• Gaps: 136/574 - (23%)

  Fly     3 AALIYTILAILLSVLATSYICIIYGVKRRVLQPVKTKNSTEINHNAYQKYTQA--PGPRPWPIIG 65
            |.:|:|.:.:||..|          |.||                  |::|..  |||.|:|.:|
Mouse    11 AVVIFTAIFLLLVDL----------VHRR------------------QRWTACYPPGPVPFPGLG 47

  Fly    66 NLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSGRPDFIRY 130
            ||..:| :.:.|:: |..|..:||:::||.......:|||.|:.:||:|...|:..|.||....|
Mouse    48 NLLQVD-FENIPYS-FYKLQNRYGNVFSLQMAWKPVVVVNGLKAVRELLVTYGEDTSDRPLMPIY 110

  Fly   131 HKLFGGERSNSLALC----DWSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEMEHWNRELGN 191
            :.:..|.:|..:.|.    :|.:              .|.||...::...:|.:.:|.|..|...
Mouse   111 NHIGYGHKSKGVILAPYGPEWRE--------------QRRFSVSTLRDFGLGKKSLEQWVTEEAG 161

  Fly   192 QLVPG------EPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQYFDEIFWEIN--QGHP 248
            .|...      .|.|..||:.||.:|:.:..:.:.||:|:|..|.::::...|...|..  .|..
Mouse   162 HLCDAFTKEAEHPFNPSPLLSKAVSNVIASLIYARRFEYEDPFFNRMLKTLKESLGEDTGFVGEV 226

  Fly   249 LDFLPWL----------YPFYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDRDFTDALL 303
            |:.:|.|          :|    .||..|       ..:.:.:|.| :.:.|..:|.||.|||.|
Mouse   227 LNAIPMLLHIPGLPDKAFP----KLNSFI-------ALVNKMLIEH-DSTWDPAQPPRDLTDAFL 279

  Fly   304 ----------KSLLEDKDVSRNTIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEEIDA 358
                      :|...||    |..|.:::.|:.|.......:...|..:..:.|:.||:.:|||.
Mouse   280 AEVEKAKGNPESSFNDK----NLRIVVIDLFMAGMVTTSTTLSWALLLMILHPDVQRRVHQEIDE 340

  Fly   359 IIEEENRSINLLDMNAMPYTMATIFEVLRYSSSPIV----PHVATEDTVISGYGVTKGTIVFINN 419
            :|... |...:.|...||||.|.|.||.|::.  ||    ||:.:.|.....:.:.|||.:..|.
Mouse   341 VIGHV-RHPEMADQARMPYTNAVIHEVQRFAD--IVPTNLPHMTSRDIKFQDFFIPKGTTLIPNL 402

  Fly   420 YVLNTSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPH--FLPFSIGK 482
            ..:...|..|..|..|.|..||:         ::|               ..:.|  |:|||.|:
Mouse   403 SSVLKDETVWEKPLRFYPEHFLD---------AQG---------------HFVKHEAFMPFSAGR 443

  Fly   483 RTCIGQNLVRGFGFLVVVNVMQRYNIS----SHNPS-----TIKISPESLALPA 527
            |:|:|:.|.|...||....::||::.|    ...||     |:.::||...|.|
Mouse   444 RSCLGEPLARMELFLFFTCLLQRFSFSVPDGQPRPSDYGIYTMPVTPEPYQLCA 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_647975.2	CYP1_2-like	89..520	CDD:410710	121/477 (25%)
Cyp2d26	NP_083838.1	CYP2D	68..495	CDD:410756	124/483 (26%)