Protein Alignment spo and Cyp2c66

DIOPT Version :9

• Sequence 1: NP_001286943.1
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001011707.1
• Gene: Cyp2c66 / 69888
• MGIID: 1917138
• Length: 490
• Species: Mus musculus
• Alignment Length: 560
• Identity: 141/560 - (25%)
• Similarity: 234/560 - (41%)
• Gaps: 122/560 - (21%)

  Fly     9 ILAILLSVLATSYICIIYGVKRRVLQPVKTKNSTEINHNAYQKYTQAPGPRPWPIIGNLHLLDRY 73
            :|.:.|.:|.|   |::       |..:..:||        |:....|||.|.|||||:..||..
Mouse     2 VLGVFLGLLLT---CLL-------LLSLWKQNS--------QRRNLPPGPTPLPIIGNILQLDLK 48

  Fly    74 RDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSGRPDF-------IRYH 131
            ..|  ......::.||.:::|..|....:|::..:.::|.|..:|:..:||..|       .|..
Mouse    49 DIS--KSLRNFSKVYGPVFTLYLGKKPAVVLHGYKAVKEALIDHGEEFAGRGTFPVADKFIRRCG 111

  Fly   132 KLFGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEMEHWNRELGNQLV-- 194
            .:|...|:       |.::              |.||...::...:|...:|...:|....||
Mouse   112 VVFSSGRT-------WKEM--------------RRFSLMTLRNFGMGKRSIEDRVQEEARCLVDE 155

  Fly   195 ----PGEPINIKPLILKACA--NMFSQYMCSLRFDYDDVDFQQIVQYFDEIF------W-EINQG 246
                .|.|.:  |..:..||  |:....:...||||.|.:|...:...:|..      | ::...
Mouse   156 LRKTKGVPCD--PTFILGCAPCNVICSIVFQNRFDYKDQEFLTFIDILNENVEILSSPWIQVCNN 218

  Fly   247 HP--LDFLPWLYPFYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDRDFTDALLKSLLED 309
            .|  :|:||      .|| .|::......:.:.:.::|:|:| |:|::.| |||.|..|..:.::
Mouse   219 FPAIIDYLP------GRH-RKLLKNFDFAKHYFLAKVIQHKE-SLDINNP-RDFIDCFLIKMEQE 274

  Fly   310 K-----DVSRNTIIFMLED-FIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEEIDAIIEEENRSIN 368
            |     :.:...:||...| |..|.......:...|..:.|..::..::|.|||.:| ..:||..
Mouse   275 KHNPKTEFTCENLIFTASDLFAAGTETTSTTLRYSLLLLLKYPEVTAKVQAEIDCVI-GRHRSPC 338

  Fly   369 LLDMNAMPYTMATIFEVLRYSS--SPIVPHVATEDTVISGYGVTKGTIVFINNYVLNTSEKFWVN 431
            :.|.::||||.|.:.|:.||..  ...:||..|.|.....|.:.|||.|..:...:...:|.::|
Mouse   339 MQDRHSMPYTDAVLHEIQRYIDLLPTSLPHAVTRDVKFREYLIPKGTTVIASLTSVLYDDKEFLN 403

  Fly   432 PKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIGKRTCIGQNLVRGFGF 496
            |:.|:|..||:.|.:     .|.||                 :|.|||.|||.|:|:.|.|...|
Mouse   404 PERFDPSHFLDESGK-----FKKSD-----------------YFFPFSTGKRICVGEGLARTELF 446

  Fly   497 LVVVNVMQRYNISSHNPSTIKISPESLALPADCFPLVLTP 536
            |.:..::|.:|:.|               |.|...|..||
Mouse   447 LFLTTILQNFNLKS---------------PVDLKDLDTTP 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_001286943.1	p450	56..540	CDD:299894	132/513 (26%)
Cyp2c66	NP_001011707.1	p450	30..487	CDD:278495	132/514 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920