Protein Alignment spo and cyp2d6

DIOPT Version :9

• Sequence 1: NP_001286943.1
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001015719.1
• Gene: cyp2d6 / 548436
• XenbaseID: XB-GENE-855872
• Length: 505
• Species: Xenopus tropicalis
• Alignment Length: 543
• Identity: 144/543 - (26%)
• Similarity: 223/543 - (41%)
• Gaps: 130/543 - (23%)

  Fly     5 LIYTILAILLSVLATSYICIIYGVKRRVLQPVKTKNSTEINHNAYQKYTQAPGPRPWPIIGNLHL 69
            :|:|:|.:||..:           |||       |..|:.          .|.|..||.:|||..
 Frog    21 IIFTLLLLLLDFM-----------KRR-------KPCTDF----------PPSPPSWPFVGNLLQ 57

  Fly    70 LDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSGRPDFIRYHKLF 134
            :| :||. ...|..|::||||:.||.......:|:|..|:|:|.|.|..:..:.||.|..|..|
 Frog    58 MD-FRDL-HNSFKQLSKQYGDVMSLRVFWKPTVVLNGFEVIKEALIQKSEDTADRPPFNLYEIL- 119

  Fly   135 GGERSNSLALC------DWSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEMEHWNRELGNQL 193
             |...|:.|:.      .|..|              |.|:...::...:|.:.:|...|:....|
 Frog   120 -GFVGNNKAVVLANYGQSWKDL--------------RRFTLSTLRDFGMGKKSLEERVRDEAGYL 169

  Fly   194 V------PGEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQYFDEIFWEINQGHP--LD 250
            .      .|.|.:...||..|.:|:....:...||:|||..|.:::...:|.....:...|  :.
 Frog   170 CDAFQSEQGGPFDPHVLINTAVSNVICSIIFGERFEYDDHKFLKLLCLIEESIKAESGPVPQIIS 234

  Fly   251 FLPWLYP-------FYQ------RHLNKIIN-----WSSTIRGFIMERIIRHRELSVDLDEPDRD 297
            .|||...       |:|      ::|.:|||     |.|           .|          .||
 Frog   235 SLPWSSKVPGLARLFFQPRIHMLQYLQEIINEHKQTWDS-----------GH----------TRD 278

  Fly   298 FTDALLKSLLEDKDV------SRNTIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEEI 356
            |.||.:..:.:.|.|      .:|.::...:.|..|.......:...|.::....|:.|::||||
 Frog   279 FIDAFMLEMKKAKGVKDSNFNDQNLLLTTADLFSAGSETTTTTLRWGLLFMLLYPDVQRKVQEEI 343

  Fly   357 DAIIEEENRSINLLDMNAMPYTMATIFEVLRYSS-SPI-VPHVATEDTVISGYGVTKGTIVFINN 419
            |.:| ...|...:.|:..||||.|.|.|:.||:. .|: |||:|..||.|.|:.:.|||::..|.
 Frog   344 DQVI-GRTRKPTMGDVLQMPYTNAVIHEIQRYADIIPLSVPHMAYRDTHIKGFFIPKGTVIMTNL 407

  Fly   420 YVLNTSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIGKRT 484
            ..:...||.|..|.:|.|..||                    |.:...:||..  |:.||.|:|.
 Frog   408 SSVLKDEKVWEKPFQFYPEHFL--------------------DRDGKFVKREA--FMAFSAGRRV 450

  Fly   485 CIGQNLVRGFGFLVVVNVMQRYN 507
            |:|:.|.|...||...:::||::
 Frog   451 CLGEQLARMELFLFFTSLLQRFS 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_001286943.1	p450	56..540	CDD:299894	134/492 (27%)
cyp2d6	NP_001015719.1	p450	52..501	CDD:306555	130/484 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000