Protein Alignment spo and Cyp2j3

DIOPT Version :10

• Sequence 1: NP_647975.2
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_786942.1
• Gene: Cyp2j3 / 313375
• RGDID: 631442
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 566
• Identity: 155/566 - (27%)
• Similarity: 237/566 - (41%)
• Gaps: 114/566 - (20%)

  Fly     2 LAALIYTILAI-LLSVLATSYICIIYGVKRRVLQPVKTKNSTEINHNAYQKYTQAPGPRPWPIIG 65
            |...|:|:|.: :|.:.|.:::.:...:|.|     :.||             ..|||...|::|
  Rat     8 LLGAIWTVLHLRILLLAAVTFLFLADFLKHR-----RPKN-------------YPPGPWRLPLVG 54

  Fly    66 NLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSGRP-DFIR 129
            .|..||  ...|........::||::.||.|.:...:||..:.||:|:..|.......|| ..:|
  Rat    55 CLFHLD--PKQPHLSLQQFVKKYGNVLSLDFANIPSVVVTGMPLIKEIFTQMEHNFLNRPVTLLR 117

  Fly   130 YHKLFGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEMEHWNRELGNQLV 194
            .| ||   ..|.|........:::||           |:...::...:|.:.:|...:|....||
  Rat   118 KH-LF---NKNGLIFSSGQTWKEQRR-----------FALMTLRNFGLGKKSLEQRIQEEAYHLV 167

  Fly   195 P------GEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQYFDE--------------I 239
            .      |.|.:....|.||.:|:........||:|.|..||::::..||              |
  Rat   168 EAIKDEGGLPFDPHFNINKAVSNIICSVTFGERFEYHDSQFQEMLRLLDEAMCLESSMMCQLYNI 232

  Fly   240 FWEINQGHPLDFLPWLYPFYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDRDFTDALLK 304
            |..|     |.:||      ..|.....||.. ::.||.:.|..||. ..|.||| |||.||.||
  Rat   233 FPRI-----LQYLP------GSHQTLFSNWRK-LKLFISDIIKNHRR-DWDPDEP-RDFIDAFLK 283

  Fly   305 SLLE--DKDVS----RNTIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEEIDAIIEEE 363
            .:.:  ||..:    .|.|...|:.|..|.......:...|..:|...::..::|.|||.:| .:
  Rat   284 EMAKYPDKTTTSFNEENLICSTLDLFFAGTETTSTTLRWALLCMALYPEVQEKMQAEIDRVI-GQ 347

  Fly   364 NRSINLLDMNAMPYTMATIFEVLRYSS-SPI-VPHVATEDTVISGYGVTKGTIVFINNYVLNTSE 426
            .|..||.|.::||||.|.|.||.|..: .|. ||.....||.::|:.:.|||::..|...|:...
  Rat   348 GRQPNLADRDSMPYTNAVIHEVQRIGNIIPFNVPREVAVDTYLAGFNLPKGTMILTNLTALHRDP 412

  Fly   427 KFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIGKRTCIGQNLV 491
            |.|..|..|||..|||..                      |.|:. ..|||||:|||.|:|:.|.
  Rat   413 KEWATPDTFNPEHFLENG----------------------QFKKR-ESFLPFSMGKRACLGEQLA 454

  Fly   492 RGFGFLVVVNVMQRY--------NISSHNPSTIKISPES---LALP 526
            |...|:.:.:::|::        .:|.....::.|||.|   .|:|
  Rat   455 RSELFIFITSLIQKFTFKPPVNEKLSLQFRMSVTISPVSHRLCAIP 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_647975.2	CYP1_2-like	89..520	CDD:410710	130/467 (28%)
Cyp2j3	NP_786942.1	CYP2J	75..496	CDD:410755	134/473 (28%)