DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spo and Cyp2j10

DIOPT Version :9

Sequence 1:	NP_001286943.1	Gene:	spo / 38631	FlyBaseID:	FBgn0003486	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_001128452.2	Gene:	Cyp2j10 / 313373	RGDID:	1563215	Length:	502	Species:	Rattus norvegicus

Alignment Length:	511	Identity:	140/511 - (27%)
Similarity:	219/511 - (42%)	Gaps:	81/511 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 PGPRPWPIIGNLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKV 120
            |||...|.:|||..||  ...|........::||::.||.||....:|:..|.||:|......:.
  Rat    45 PGPWRLPFVGNLFQLD--VKQPHVVIQKFVKKYGNLTSLDFGTIPSVVITGLPLIKEAFTNTEQN 107

  Fly   121 MSGRPDFIRYHKLFGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEMEHW 185
            ...||......::|   .:|.|.:.:....:::||           |:...:|...:|...:|..
  Rat   108 FLNRPVTPLRKRVF---NNNGLIMSNGQTWKEQRR-----------FTMTTLKNFGLGKRSLEQR 158

  Fly   186 NRELGNQLV------PGEPINIKPLILKACANMFSQYMCSL----RFDYDDVDFQQIVQYFDE-- 238
            .:|..|.||      .|:|.:....|..|.:|:    :||:    ||:|:|..||::::..||
  Rat   159 IQEEANYLVEAIGADKGQPFDPHFKINSAVSNI----ICSITFGERFEYEDSLFQELLRLLDEAS 219

  Fly   239 -----IFWEINQGHP--LDFLPWLYPFYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDR 296
                 :..::....|  :.:||      ..|...:.||.. ::.||...:..|:: ..:.||| |
  Rat   220 CLESSMMCQLYNVFPTIIKYLP------GSHQTVLRNWEK-LKLFISCMMDSHQK-DWNPDEP-R 275

  Fly   297 DFTDALLKSLLEDKDVS------RNTIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEE 355
            ||.||.|..:.:.:|.:      .|.|...|:.|..|.....|::...|.||..|.::..::..|
  Rat   276 DFIDAFLTEMAKYRDKTTTSFNKENLIYSTLDLFFAGSETTSNILRWSLLYITTNPEVQEKVHSE 340

  Fly   356 IDAIIEEENRSINLLDMNAMPYTMATIFEVLRYSS-SPI-VPHVATEDTVISGYGVTKGTIVFIN 418
            ||.:| ...|..:..|.:|||||.|.|.||||..: .|: ||...|.|:.::|:.:.|||.:..|
  Rat   341 IDRVI-GHRRQPSTGDRDAMPYTNAVIHEVLRMGNIIPLNVPREMTADSTLAGFHLPKGTTILTN 404

  Fly   419 NYVLNTSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIGKR 483
            ...|:...|.|..|..|||..|||..:      .|..||                 |||||:|||
  Rat   405 LTGLHRDPKEWATPDTFNPEHFLENGQ------FKKRDS-----------------FLPFSMGKR 446

  Fly   484 TCIGQNLVRGFGFLVVVNVMQRYNISSHNPSTIKIS-PESLALPADCFPLVLTPRE 538
            .|.|:.|.|...|:....:||.:........|:.:. ...|.|......:...||:
  Rat   447 ACPGEQLARTELFIFFTALMQNFTFKPPVNETLSLKFRNGLTLAPVSHRICAVPRQ 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_001286943.1	p450	56..540	CDD:299894	140/511 (27%)
Cyp2j10	NP_001128452.2	cytochrome_P450	75..496	CDD:425388	128/471 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920