Protein Alignment spo and Cyp2b12

DIOPT Version :10

• Sequence 1: NP_647975.2
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_058852.2
• Gene: Cyp2b12 / 29295
• RGDID: 620088
• Length: 492
• Species: Rattus norvegicus
• Alignment Length: 506
• Identity: 135/506 - (26%)
• Similarity: 215/506 - (42%)
• Gaps: 103/506 - (20%)

  Fly    56 PGPRPWPIIGNLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKV 120
            |||||.|.:||  ||...|......|..|.::|||::::..|....:::...:.|||.|....:.
  Rat    33 PGPRPLPFLGN--LLQMNRRGFLNSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEA 95

  Fly   121 MSGR-------PDFIRYHKLFG-GERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYMKMSQI 177
            .|||       |....|..:|. |||        |..|              |.||...||...:
  Rat    96 FSGRGTVAVLHPVVQGYGVIFATGER--------WKTL--------------RRFSLVTMKEFGM 138

  Fly   178 GCEEMEHWNRELGNQLV------PGEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQYF 236
            |...::...:|....||      .|.|:|...|.....||.....:...||||.|   .|.:...
  Rat   139 GKRSVDERIKEEAQCLVEELKKYKGAPLNPTFLFQSIAANTICSIVFGERFDYKD---HQFLHLL 200

  Fly   237 DEIF-------------WEINQGHPLDFLPWLYPFYQRHLNKIINWSSTIRGFIMERIIRHRELS 288
            |.::             :|:..|. |.:.|..:....::|.:::|:.    |.|:|   :|| .:
  Rat   201 DLVYKTSVLMGSLSSQVFELYSGF-LKYFPGAHKQIFKNLQEMLNYI----GHIVE---KHR-AT 256

  Fly   289 VDLDEPDRDFTDALLKSLLEDKD------VSRNTIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVD 347
            :|...| |||.|..|..:.::|.      ..:|.:|.:|..|..|.......:......:.|...
  Rat   257 LDPSAP-RDFIDTYLLRMEKEKSNHHTEFNHQNLVISVLSLFFAGTETTSTTLRCTFLIMLKYPH 320

  Fly   348 IGRRIQEEIDAIIEEENRSINLLDMNAMPYTMATIFEVLRYSS-SPI-VPHVATEDTVISGYGVT 410
            :..::|:|||.:| ..:|.....|...||||.|.|.|:.|::. :|| :||..|:|||..||.:.
  Rat   321 VAEKVQKEIDQVI-GSHRLPTPDDRTKMPYTDAVIHEIQRFADLTPIGLPHRVTKDTVFRGYLLP 384

  Fly   411 KGTIVF-INNYVLNTSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPH 474
            |.|.|: |.:..|: ..:::..|..|||..||:         :.|:            ||:: ..
  Rat   385 KNTEVYPILSSALH-DPRYFEQPDTFNPEHFLD---------ANGA------------LKKS-EA 426

  Fly   475 FLPFSIGKRTCIGQNLVRGFGFLVVVNVMQRYNISSHNPSTIKISPESLAL 525
            |||||.|||.|:|:.:.|...|:....::|.:.::|      .::||.:.|
  Rat   427 FLPFSTGKRICLGEGIARNELFIFFTAILQNFTLAS------PVAPEDIDL 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_647975.2	CYP1_2-like	89..520	CDD:410710	118/466 (25%)
Cyp2b12	NP_058852.2	CYP2B	63..487	CDD:410765	122/474 (26%)