Protein Alignment spo and Cyp2d5

DIOPT Version :10

• Sequence 1: NP_647975.2
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_775426.1
• Gene: Cyp2d5 / 286963
• RGDID: 628630
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 566
• Identity: 139/566 - (24%)
• Similarity: 246/566 - (43%)
• Gaps: 109/566 - (19%)

  Fly     6 IYTILAILLSVLATSYICIIYGVKRRVLQPVKTKNSTEINHNAYQKYTQ--APGPRPWPIIGNLH 68
            |:|::.|||                           .::.|. :|::|.  .|||.|||::|||.
  Rat    14 IFTVIFILL---------------------------VDLMHR-HQRWTSRYPPGPVPWPVLGNLL 50

  Fly    69 LLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSGRPDFIRYHKL 133
            .:|. .:.|::.: .|..:|||::||..|....::||.|:.::|||..:|:..:.||....:..|
  Rat    51 QVDP-SNMPYSMY-KLQHRYGDVFSLQMGWKPMVIVNRLKAVQEVLVTHGEDTADRPPVPIFKCL 113

  Fly   134 FGGERSNSLALCDWS-QLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEMEHW-NRELGN----- 191
            ....||..:....:. :.:::||           ||...::...:|.:.:|.| .:|.|:
  Rat   114 GVKPRSQGVVFASYGPEWREQRR-----------FSVSTLRTFGMGKKSLEEWVTKEAGHLCDAF 167

  Fly   192 QLVPGEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQYFDEIFWEINQGHPLDFLPWLY 256
            ....|..||.|.::.||..|:.:..:.:.||:|:|....:::...:|...|::     .|:|.:.
  Rat   168 TAQNGRSINPKAMLNKALCNVIASLIFARRFEYEDPYLIRMLTLVEESLIEVS-----GFIPEVL 227

  Fly   257 PFYQRHL------NKIINWSSTIRGFIMERIIRHRELSVDLDEPDRDFTDALL------KSLLED 309
            ..:...|      :|:.....|...| ::.::.....:.|..:|.|:.|||.|      |...|.
  Rat   228 NTFPALLRIPGLADKVFQGQKTFMAF-LDNLLAENRTTWDPAQPPRNLTDAFLAEVEKAKGNPES 291

  Fly   310 KDVSRNTIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEEIDAIIEEENRSINLLDMNA 374
            .....|..:.:::.|..|.......:...|..:....|:.||:|:|||.:|.:. |...:.|...
  Rat   292 SFNDENLRMVVVDLFTAGMVTTATTLTWALLLMILYPDVQRRVQQEIDEVIGQV-RCPEMTDQAH 355

  Fly   375 MPYTMATIFEVLRYSS-SPI-VPHVATEDTVISGYGVTKGTIVFINNYVLNTSEKFWVNPKEFNP 437
            ||||.|.|.||.|:.. :|: :|.:.:.|..:..:.:.|||.:.||...:...|..|..|..|:|
  Rat   356 MPYTNAVIHEVQRFGDIAPLNLPRITSCDIEVQDFVIPKGTTLIINLSSVLKDETVWEKPLRFHP 420

  Fly   438 LRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIGKRTCIGQNLVRGFGFLVVVNV 502
            ..||:         ::|:....|:             |:|||.|:|.|:|:.|.|...||....:
  Rat   421 EHFLD---------AQGNFVKHEA-------------FMPFSAGRRACLGEPLARMELFLFFTCL 463

  Fly   503 MQRYNIS----SHNPST-----IKISPESLALPADCFPLVLTPREK 539
            :|.::.|    ...|||     |.::|    ||   :.|....||:
  Rat   464 LQHFSFSVPAGQPRPSTLGNFAISVAP----LP---YQLCAAVREQ 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_647975.2	CYP1_2-like	89..520	CDD:410710	112/460 (24%)
Cyp2d5	NP_775426.1	CYP2D	68..495	CDD:410756	116/473 (25%)