DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spo and Cyp2g1

DIOPT Version :9

Sequence 1:	NP_001286943.1	Gene:	spo / 38631	FlyBaseID:	FBgn0003486	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_036919.1	Gene:	Cyp2g1 / 25251	RGDID:	2477	Length:	494	Species:	Rattus norvegicus

Alignment Length:	501	Identity:	138/501 - (27%)
Similarity:	217/501 - (43%)	Gaps:	93/501 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 PGPRPWPIIGNLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKV 120
            |||.|.|.:||  ||....|:.|..|..|.::||.::::.||....:::...|.::|.|......
  Rat    35 PGPTPIPFLGN--LLQVRIDATFQSFLKLQKKYGSVFTVYFGPRPVVILCGHEAVKEALVDQADD 97

  Fly   121 MSGRPDFIRYHKLFGGERSNSLALCD---WSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEM 182
            .|||.:.....|.|.|   ..|||.:   |..|              |.||...::...:|...:
  Rat    98 FSGRGEMPTLEKNFQG---YGLALSNGERWKIL--------------RRFSLTVLRNFGMGKRSI 145

  Fly   183 EHWNRELGNQL------VPGEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQYFDEIFW 241
            |...:|....|      |.|.||:....:.:..:|:....:...||||:|..|:.:::..:|.|.
  Rat   146 EERIQEEAGYLLEELHKVKGAPIDPTFYLSRTVSNVICSVVFGKRFDYEDQRFRSLMKMINESFV 210

  Fly   242 EINQGHPLDFLPW--LYPFY--------QRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDR 296
            |::       :||  ||..|        .|| |::.|....::.||..| ::..|.|.|...| |
  Rat   211 EMS-------MPWAQLYDMYWGVIQYFPGRH-NRLYNLIEELKDFIASR-VKINEASFDPSNP-R 265

  Fly   297 DFTDALLKSLLEDKDVS------RNTIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEE 355
            ||.|..|..:.:||...      :|.::..|..|..|...|.:.:......:.|..::..:|.||
  Rat   266 DFIDCFLIKMYQDKSDPHSEFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLLMKYPEVEAKIHEE 330

  Fly   356 IDAIIEEENRSINLLDMNAMPYTMATIFEVLRYSS-SPI-VPHVATEDTVISGYGVTKGTIVF-I 417
            |:.:| ..:|:..:.|...||||.|.|.|:.|.:. .|: |||....||...||.:.|||.|: :
  Rat   331 INQVI-GTHRTPRVDDRAKMPYTDAVIHEIQRLTDIVPLGVPHNVIRDTHFRGYFLPKGTDVYPL 394

  Fly   418 NNYVLNTSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIGK 482
            ...||. ..|::..|:.|.|..||:                     |:.:.|:| ..|:.||.||
  Rat   395 IGSVLK-DPKYFRYPEAFYPQHFLD---------------------EQGRFKKN-DAFVAFSSGK 436

  Fly   483 RTCIGQNLVRGFGFLVVVNVMQRYNISSHNPSTIKISPESLALPAD 528
            |.|:|:.|.|...||...:::||:::            .||..|||
  Rat   437 RICVGEALARMELFLYFTSILQRFSL------------RSLVPPAD 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_001286943.1	p450	56..540	CDD:299894	138/501 (28%)
Cyp2g1	NP_036919.1	p450	34..491	CDD:278495	138/501 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010