Protein Alignment spo and Cyp17a1

DIOPT Version :10

• Sequence 1: NP_647975.2
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_036885.2
• Gene: Cyp17a1 / 25146
• RGDID: 2456
• Length: 507
• Species: Rattus norvegicus
• Alignment Length: 518
• Identity: 129/518 - (24%)
• Similarity: 225/518 - (43%)
• Gaps: 73/518 - (14%)

  Fly    53 TQAPG---PR---PWPIIGNLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIR 111
            ::.||   ||   ..|::|:|..|.| |......|..|.::||.||||..|.|..:::.:.:|.|
  Rat    20 SKTPGAKLPRSLPSLPLVGSLPFLPR-RGHMHVNFFKLQEKYGPIYSLRLGTTTTVIIGHYQLAR 83

  Fly   112 EVLNQNGKVMSGRPDFIRYHKLFGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYM---- 172
            |||.:.||..||||..:....|  .::...:|..|........|.|.        ||.|.:
  Rat    84 EVLIKKGKEFSGRPQMVTQSLL--SDQGKGVAFADAGSSWHLHRKLV--------FSTFSLFKDG 138

  Fly   173 -KMSQIGCEEMEHWNRELGNQLV--PGEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQ 234
             |:.::.|:|.    :.|.:.::  ..|.|::...|..:..|:......::.::..|.....|..
  Rat   139 QKLEKLICQEA----KSLCDMMLAHDKESIDLSTPIFMSVTNIICAICFNISYEKKDPKLTAIKT 199

  Fly   235 YFDEIFWEINQGHPLDFLPWLYPFYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDRDFT 299
            :.:.|.......:.:|..|||..|..:.| ::|...:.:|..::..|........| .:.....|
  Rat   200 FTEGIVDATGDRNLVDIFPWLTIFPNKGL-EVIKGYAKVRNEVLTGIFEKCREKFD-SQSISSLT 262

  Fly   300 DALLKSLL----------EDKDV-SRNTIIFMLEDFIG-GHSAVGNLVMLVLAYIAKNVDIGRRI 352
            |.|:::.:          .|.|| |...|:..:.|..| |......::..:||::..|.::.::|
  Rat   263 DILIQAKMNSDNNNSCEGRDPDVFSDRHILATVGDIFGAGIETTTTVLKWILAFLVHNPEVKKKI 327

  Fly   353 QEEIDAIIEEENRSINLLDMNAMPYTMATIFEVLRYS--SSPIVPHVATEDTVISGYGVTKGTIV 415
            |:|||..: ..:|:....|.:.:....|||.||||..  :..::||.|..|:.|..:.|.|.|.|
  Rat   328 QKEIDQYV-GFSRTPTFNDRSHLLMLEATIREVLRIRPVAPMLIPHKANVDSSIGEFTVPKDTHV 391

  Fly   416 FINNYVLNTSEKFWVNPKEFNPLRFLEPSKEQ--SPKNSKGSDSGIESDNEKLQLKRNIPHFLPF 478
            .:|.:.|:..|..|..|.:|.|.|||:|:...  :|..|                      :|||
  Rat   392 VVNLWALHHDENEWDQPDQFMPERFLDPTGSHLITPTQS----------------------YLPF 434

  Fly   479 SIGKRTCIGQNLVRGFGFLVVVNVMQRYNISSHNPS---TIKISPESLALPADCFPLVLTPRE 538
            ..|.|:|||:.|.|...|:....::||:::...:..   .::..|:.:.| .|.|.:.:|.|:
  Rat   435 GAGPRSCIGEALARQELFVFTALLLQRFDLDVSDDKQLPRLEGDPKVVFL-IDPFKVKITVRQ 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_647975.2	CYP1_2-like	89..520	CDD:410710	110/456 (24%)
Cyp17a1	NP_036885.2	CYP17A1	60..490	CDD:410766	115/469 (25%)