Protein Alignment spo and Cyp2r1

DIOPT Version :10

• Sequence 1: NP_647975.2
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_796356.2
• Gene: Cyp2r1 / 244209
• MGIID: 2449771
• Length: 501
• Species: Mus musculus
• Alignment Length: 487
• Identity: 137/487 - (28%)
• Similarity: 219/487 - (44%)
• Gaps: 82/487 - (16%)

  Fly    56 PGPRPWPIIGNLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKV 120
            |||...|.:||:..|....|.|.......::.||:|:||..|....:|:|..::::|.|....::
Mouse    41 PGPPRLPFVGNICSLALSADLPHVYMRKQSRVYGEIFSLDLGGISTVVLNGYDVVKECLVHQSEI 105

  Fly   121 MSGRPD---FIRYHKLFGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEM 182
            .:.||.   |::..|:  |...||.....|..    .|.||..       |..|....|...|..
Mouse   106 FADRPCLPLFMKMTKM--GGLLNSRYGRGWID----HRRLAVN-------SFHYFGSGQKSFESK 157

  Fly   183 ---EHWNRELGNQLVPGEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQYFDEIFWEIN 244
               |.|:.....:...|.|.::|.||..|.:|:.:..:...||.|:|.|||.:::.|.|.. |:.
Mouse   158 ILEETWSLIDAIETYKGGPFDLKQLITNAVSNITNLILFGERFTYEDTDFQHMIELFSENV-ELA 221

  Fly   245 QGHPLDFL----PW--LYPF--YQR----------HLNKIINWSSTIRGFIMERIIRHRELSVDL 291
            ...|: ||    ||  :.||  :||          .|:::|..::..|    :..:.|..:...|
Mouse   222 ASAPV-FLYNAFPWIGILPFGKHQRLFRNADVVYDFLSRLIEKAAVNR----KPHLPHHFVDAYL 281

  Fly   292 DEPDRDFTDALLKSLLEDKDVSRNTIIFML-EDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEE 355
            ||.|:...|.|       ...|:..:||.: |..|.|.....|::...:.::|...:|..::.:|
Mouse   282 DEMDQGQNDPL-------STFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVHKE 339

  Fly   356 IDAIIEEENRSINLLDMNAMPYTMATIFEVLRYSSSPIVP----HVATEDTVISGYGVTKGTIVF 416
            ||.|: ..||..:......||||.|.:.||||:.:  |||    |..:||.|:.||.:.|||.|.
Mouse   340 IDLIV-GHNRRPSWEYKCKMPYTEAVLHEVLRFCN--IVPLGIFHATSEDAVVRGYSIPKGTTVI 401

  Fly   417 INNYVLNTSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIG 481
            .|.|.::..||:|.:|..|.|.|||:             .:|..:..|.|         :|||:|
Mouse   402 TNLYSVHFDEKYWKDPDMFYPERFLD-------------SNGYFTKKEAL---------IPFSLG 444

  Fly   482 KRTCIGQNLVRGFGFLVVVNVMQRYNISSHNP 513
            :|.|:|:.|.|...||...:::|::::  |.|
Mouse   445 RRHCLGEQLARMEMFLFFTSLLQQFHL--HFP 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_647975.2	CYP1_2-like	89..520	CDD:410710	127/454 (28%)
Cyp2r1	NP_796356.2	cytochrome_P450	62..497	CDD:477761	129/466 (28%)