Protein Alignment spo and Cyp21a1

DIOPT Version :10

• Sequence 1: NP_647975.2
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_476442.2
• Gene: Cyp21a1 / 24298
• RGDID: 2461
• Length: 493
• Species: Rattus norvegicus
• Alignment Length: 515
• Identity: 129/515 - (25%)
• Similarity: 210/515 - (40%)
• Gaps: 124/515 - (24%)

  Fly    65 GNLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSGRPDFIR 129
            |.||.|.  .:.|...| .|||:.|.||.:..|....:|:|:.:.|.|.|.|.....:|||
  Rat    38 GFLHFLQ--PNLPVYLF-GLAQKLGPIYRIRLGLQDVVVLNSNKTIEEALIQKWVDFAGRP---- 95

  Fly   130 YHKLFGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEMEHWNRELGNQLV 194
              ::..|:.:..|::.|:|...:..:.|:|                               :.||
  Rat    96 --QILDGKMNFDLSMGDYSLTWKAHKKLSR-------------------------------SALV 127

  Fly   195 PGEPINIKPLI----LKACANM-------------FSQYMCS----LRF-DYDDVDF-------- 229
            .|...:::||:    .:.|..|             ||...||    |.| |..|...
  Rat   128 LGMRDSMEPLVEQLTQEFCERMRAQAGASVAIHKEFSLLTCSIISCLTFGDKQDSTLLNATHSCV 192

  Fly   230 QQIVQYFDEIFWEINQGHPLDFLPWLYPFYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEP 294
            :.:::.::.  |.:   ..||.:|:|..|....|.|:..:..:....:|:.:.||::..|  ...
  Rat   193 RDLLKAWNH--WSV---QILDIIPFLRFFPNPGLWKLKQFQESRDHIVMQELKRHKDSLV--AGQ 250

  Fly   295 DRDFTDALLKSLLEDKDV-------SRNTIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRI 352
            .:|..|.:|:.:.:.:|.       .|:..:.:::.|:||.......:...:|::..:.:|.:|:
  Rat   251 WKDMIDYMLQGVEKQRDARDPGQLHERHVHMSVVDLFVGGTETTAATLSWAVAFLLHHPEIQKRL 315

  Fly   353 QEEIDAIIEEENRSINLLDMNAM--PYTMATIFEVLRYSSSPIV----PHVATEDTVISGYGVTK 411
            |||:|..:..   |..||..|.|  |..||||.||||.  .|:|    ||.||:.:.||||.:.|
  Rat   316 QEELDLKLAP---SSQLLYKNRMQLPLLMATIAEVLRL--RPVVPMALPHRATKASSISGYDIPK 375

  Fly   412 GTIVFINNYVLNTSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFL 476
            .||:..|....|..|..|..|.:|.|.||||..|  ||:                     ||
  Rat   376 DTIIIPNIQGANLDEMVWELPSKFWPDRFLESGK--SPR---------------------IP--- 414

  Fly   477 PFSIGKRTCIGQNLVRGFGFLVVVNVMQRYNISSHNPSTIKISPESLALPADCFPLVLTP 536
            .|..|.|.|:|:.|.|...|:|:..::|.:.:......|:   |....||.....|::.|
  Rat   415 TFGCGARVCLGEPLARLELFVVLARLLQTFTLLPPPDGTL---PSLQPLPYTGINLLIPP 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_647975.2	CYP1_2-like	89..520	CDD:410710	115/473 (24%)
Cyp21a1	NP_476442.2	CYP21	58..477	CDD:410767	120/492 (24%)