Protein Alignment spo and Cyp2j12

DIOPT Version :10

• Sequence 1: NP_647975.2
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001093652.1
• Gene: Cyp2j12 / 242546
• MGIID: 3717097
• Length: 502
• Species: Mus musculus
• Alignment Length: 505
• Identity: 138/505 - (27%)
• Similarity: 219/505 - (43%)
• Gaps: 89/505 - (17%)

  Fly    48 AYQKYTQAP---GPRPW--PIIGNLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNL 107
            |:...||.|   .|.||  |.:|||..||  .:.|........::||::.||.||:...:::..|
Mouse    32 AHYLKTQRPKNYPPGPWRLPFVGNLFQLD--LEQPHVVIQQFVKKYGNLTSLDFGNIPSVIITGL 94

  Fly   108 ELIREVLNQNGKVMSGRPDFIRYHKLFGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYM 172
            .||:||.....:....||......::|   .:|.|.:.:....:::||           |:...:
Mouse    95 PLIKEVFTNMEQNFLNRPITPIRKRVF---NNNGLIISNGQTWKEQRR-----------FALMTL 145

  Fly   173 KMSQIGCEEMEHWNRELGNQLV------PGEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQ 231
            |...:|.:.:|...::..:.||      .|:|.:....|..|.:|:...:....||:|:|..|.:
Mouse   146 KNFGLGKKSLEQRIQKEADCLVEAIGEEKGQPFDPHFKINSAVSNIICTFAFGERFEYEDSHFHE 210

  Fly   232 IVQYFDE--------------IFWEINQGHPLDFLPWLYPFYQRHLNKIINWSSTIRGFIMERII 282
            :::..||              :|..|     :.::|      ..|...:.||.. ::.||.:.:.
Mouse   211 LLRLLDEATCLEASMMCQLYNVFPSI-----IQYVP------GSHQTVLRNWEK-LKLFIYQMME 263

  Fly   283 RHRELSVDLDEPDRDFTDALLKSLLE--DKDVS----RNTIIFMLEDFIGGHSAVGNLVMLVLAY 341
            .||: ..:.||| |||.||.|..:.:  ||..:    .|.|...|:.|..|.....|.:...|.|
Mouse   264 SHRK-DWNPDEP-RDFIDAFLTEMSKYGDKTTTSFNEENLINSTLDLFFAGSETTTNTLRWALLY 326

  Fly   342 IAKNVDIGRRIQEEIDAIIEEENRSINLLDMNAMPYTMATIFEVLRYSS-SPI-VPHVATEDTVI 404
            |..|.::..::..|||.:| ...|..:..|.::||||.|.|.||||..: .|: ||...|.|:.:
Mouse   327 ITTNPEVQEKVHSEIDRVI-GHGRQPSTDDRDSMPYTNAVIHEVLRMGNILPMNVPREVTADSTL 390

  Fly   405 SGYGVTKGTIVFINNYVLNTSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLK 469
            :|:.:.|||:|..|...|:...|.|..|..|||..|||..                      |.|
Mouse   391 AGFHLPKGTMVLTNLTALHRDPKEWATPNTFNPEHFLENG----------------------QFK 433

  Fly   470 RNIPHFLPFSIGKRTCIGQNLVRGFGFLVVVNVMQRYNISSHNPSTIKIS 519
            :. ..|||||:|||.|.|:.|.|...|:....:||::....  |...|:|
Mouse   434 KR-ESFLPFSLGKRACPGEQLARSELFIFFTALMQKFTFKP--PINEKLS 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_647975.2	CYP1_2-like	89..520	CDD:410710	123/459 (27%)
Cyp2j12	NP_001093652.1	cytochrome_P450	75..496	CDD:477761	124/460 (27%)