Protein Alignment spo and Cyp2j6

DIOPT Version :10

• Sequence 1: NP_647975.2
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_034138.3
• Gene: Cyp2j6 / 13110
• MGIID: 1270148
• Length: 501
• Species: Mus musculus
• Alignment Length: 566
• Identity: 160/566 - (28%)
• Similarity: 248/566 - (43%)
• Gaps: 93/566 - (16%)

  Fly     1 MLAA---LIYTILAIL----LSVLATSYICIIYGVKRRVLQPVKTKNSTEINHNAYQKYTQAPGP 58
            ||||   |:.||.|.|    |.|.|.:::.:....|.|     :.||             ..|||
Mouse     1 MLAATGSLLATIWAALHPRTLLVAAVTFLLLADYFKNR-----RPKN-------------YPPGP 47

  Fly    59 RPWPIIGNLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSG 123
            ...|.:||:..||  ...|......|.::||:|:||..|....:|:..|.||:|.|.|..:.:..
Mouse    48 WGLPFVGNIFQLD--FGQPHLSIQPLVKKYGNIFSLNLGDITSVVITGLPLIKEALTQMEQNIMN 110

  Fly   124 RPDFIRYHKLFGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEMEHWNRE 188
            ||..:...::   ...|.|........:::||           |:...::...:|.:.:|...:|
Mouse   111 RPLSVMQERI---SNKNGLIFSSGQIWKEQRR-----------FALMTLRNFGLGKKSLEERMQE 161

  Fly   189 LGNQLV------PGEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQYFDEIFW----EI 243
            ..:.||      .|:|.|....|..|.:|:........||||.|..||::::..||:.:    .|
Mouse   162 EASHLVEAIREEEGKPFNPHFSINNAVSNIICSVTFGERFDYHDSRFQEMLRLLDEVMYLETTMI 226

  Fly   244 NQGHPLDFLPWLYPFYQRHLNKII-NWSSTIRGFIMERIIRHRELSVDLDEPDRDFTDALLKSLL 307
            :|.:  :..||:..:......|:. ||.. ::.|:...|..||: ..:.||| |||.||.||.:.
Mouse   227 SQLY--NIFPWIMKYIPGSHQKVFRNWEK-LKLFVSCMIDDHRK-DWNPDEP-RDFIDAFLKEMT 286

  Fly   308 E--DKDVS---RNTIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEEIDAIIEEENRSI 367
            :  :|..|   .|.|...|:.|..|.......:...|.|:|...::..::|.|||.:|.:: |:.
Mouse   287 KYPEKTTSFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQK-RAA 350

  Fly   368 NLLDMNAMPYTMATIFEVLRYSS-SPI-VPHVATEDTVISGYGVTKGTIVFINNYVLNTSEKFWV 430
            .|.|..:||||.|.|.||.|..: .|: ||.....||.::|:.:.|||:|..|...|:...|.|.
Mouse   351 RLADRESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWA 415

  Fly   431 NPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIGKRTCIGQNLVRGFG 495
            .|..|||..|||..                      |.|:. ..|||||:|||.|:|:.|.|...
Mouse   416 TPDVFNPEHFLENG----------------------QFKKR-ESFLPFSMGKRACLGEQLARSEL 457

  Fly   496 FLVVVNVMQRYNISSHNPSTIKISPE---SLALPADCFPLVLTPRE 538
            |:...::||::..:.  |...|:||:   .|.|......:...||:
Mouse   458 FIFFTSLMQKFTFNP--PINEKLSPKFRNGLTLSPVSHRICAVPRQ 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_647975.2	CYP1_2-like	89..520	CDD:410710	127/448 (28%)
Cyp2j6	NP_034138.3	CYP2J	75..495	CDD:410755	132/464 (28%)