Protein Alignment spo and Cyp2c40

DIOPT Version :10

• Sequence 1: NP_647975.2
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_034134.3
• Gene: Cyp2c40 / 13099
• MGIID: 1306815
• Length: 491
• Species: Mus musculus
• Alignment Length: 502
• Identity: 142/502 - (28%)
• Similarity: 224/502 - (44%)
• Gaps: 96/502 - (19%)

  Fly    56 PGPRPWPIIGNLHLLDRYRDSPFAG--FTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNG 118
            |||.|.|||||.||:| .:|   .|  .|..::.||.:::|.||....:|::..|.|:|.|..:|
Mouse    31 PGPTPLPIIGNYHLID-MKD---IGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHG 91

  Fly   119 KVMSGRP-----DFIRYHKLFGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYMKMSQIG 178
            :..|||.     |.:...|..|....|.     |.              :.|.|:...::...:|
Mouse    92 EEFSGRGRIPVFDKVSTGKGIGFSHGNV-----WK--------------ATRVFTVNTLRNLGMG 137

  Fly   179 CEEMEHWNRELGNQLVP------GEPINIKPLILKACA--NMFSQYMCSLRFDYDDVDFQQIVQY 235
            ...:|:..:|....|:.      |.|.:  |..:..||  |:....:...||||.|.||..::..
Mouse   138 KRTIENKVQEEAQWLMKELKKTNGSPCD--PQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGK 200

  Fly   236 FDE-----------IFWEINQGHPLDFLPWLYPFYQRHLNKIINWSSTIRGFIMERIIRHRELSV 289
            .:|           ||         :.:|.|..:.....||:....:.|:.:::.:|..|.| |:
Mouse   201 VNECTEILSSPGCQIF---------NAVPILIDYCPGSHNKLFKNHTWIKSYLLGKIKEHEE-SL 255

  Fly   290 DLDEPDRDFTDALL-----KSLLEDKDVSRNTIIFMLEDFI-GGHSAVGNLVMLVLAYIAKNVDI 348
            |:..| |||.|..|     |:.:|..|.:...:..::.|.: ||...:.:.:...|..:.|:..|
Mouse   256 DVTNP-RDFIDYFLIQRRQKNGIEHMDYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHI 319

  Fly   349 GRRIQEEIDAIIEEENRSINLLDMNAMPYTMATIFEVLRY-SSSPI-VPHVATEDTVISGYGVTK 411
            ..::|||||.:| ..:||..:.|.|.||||.|.:.||.|| ...|. |.|..|.||....|.:.|
Mouse   320 TAKVQEEIDNVI-GRHRSPCMQDRNHMPYTNAMVHEVQRYIDLGPNGVVHEVTCDTKFRNYFIPK 383

  Fly   412 GTIVFIN-NYVLNTSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHF 475
            ||.|..: ..||:.|.:| .||:.|:|..||:.:     .|.|.||                 :|
Mouse   384 GTQVMTSLTSVLHDSTEF-PNPEVFDPGHFLDDN-----GNFKKSD-----------------YF 425

  Fly   476 LPFSIGKRTCIGQNLVRGFGFLVVVNVMQRYNISS-HNPSTIKISPE 521
            :|||.|||.|:|::|.|...||.:..::|.:.:.. .:|..|.::|:
Mouse   426 VPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDMTPK 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_647975.2	CYP1_2-like	89..520	CDD:410710	125/464 (27%)
Cyp2c40	NP_034134.3	CYP2C-like	61..485	CDD:410758	127/468 (27%)