Protein Alignment spo and Cyp2c37

DIOPT Version :10

• Sequence 1: NP_647975.2
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_034131.2
• Gene: Cyp2c37 / 13096
• MGIID: 1306806
• Length: 490
• Species: Mus musculus
• Alignment Length: 515
• Identity: 146/515 - (28%)
• Similarity: 235/515 - (45%)
• Gaps: 90/515 - (17%)

  Fly    56 PGPRPWPIIGNLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKV 120
            |||.|.|||||:..:| .:|. ...||.|::.||.:|:|..|....:|::..|.::|.|..:|:.
Mouse    31 PGPTPLPIIGNILQID-VKDI-CQSFTNLSKVYGPVYTLYLGRKPTVVLHGYEAVKEALVDHGEE 93

  Fly   121 MSGRPDFIRYHKLFGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEMEHW 185
            .:||..|..:.|...|   ..||....:..:..||           ||...::...:|...:|..
Mouse    94 FAGRGRFPVFDKATNG---MGLAFSKGNVWKNTRR-----------FSLMTLRNLGMGKRSIEDR 144

  Fly   186 NRELGNQLVP------GEPINIKPLILKACANMFSQYMCSL----RFDYDDVDFQQIVQYFDEIF 240
            .:|....||.      |.|.:  |..:..||.  ...:||:    ||||.|.||..:::..:||.
Mouse   145 VQEEARCLVEELRKTNGSPCD--PTFILGCAP--CNVICSIIFQDRFDYKDRDFLNLMEKLNEIT 205

  Fly   241 ------W-EINQGHP--LDFLPWLY-PFYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPD 295
                  | :|...:|  ||:.|..: .|::.:        ::|:.|::|:|..|.| |:|:..|
Mouse   206 KILSSPWLQICNTYPALLDYCPGSHKQFFKNY--------ASIKNFLLEKIKEHEE-SLDVTIP- 260

  Fly   296 RDFTD-ALLKSLLED-----KDVSRNTIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQE 354
            |||.| .|:....||     ::...:..|.:.:.|..|.......:...:..:.|...:..::||
Mouse   261 RDFIDYFLINGGQEDGNQPLQNRLEHLAITVTDLFSAGTETTSTTLRYAILLLLKYPHVTAKVQE 325

  Fly   355 EIDAIIEEENRSINLLDMNAMPYTMATIFEVLRYSS--SPIVPHVATEDTVISGYGVTKGTIVFI 417
            ||:.:| .::||..:.|.:.||||.|.|.||.|:..  ...:||..|.|.....|.:.|||.|..
Mouse   326 EIEHVI-GKHRSPCMQDRSRMPYTDAMIHEVQRFIDLIPNSLPHEVTSDIKFRNYFIPKGTTVIT 389

  Fly   418 N-NYVLNTSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIG 481
            : :.||:.|.:| .||::|:|..||:       :|.|...|               .:|:|||.|
Mouse   390 SLSSVLHDSTEF-PNPEKFDPGHFLD-------ENGKFKKS---------------DYFIPFSTG 431

  Fly   482 KRTCIGQNLVRGFGFLVVVNVMQRYNISS-HNPSTIKISPESLAL----PADCFPLVLTP 536
            ||.|.|:.|.|...||.:.:::|.:|:.. .:|..|.::|..:.|    ||  |.|...|
Mouse   432 KRICAGEGLARMELFLFLTSILQNFNLKPLVHPKDIDVTPMLIGLASVPPA--FQLCFIP 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_647975.2	CYP1_2-like	89..520	CDD:410710	124/460 (27%)
Cyp2c37	NP_034131.2	CYP2C-like	61..485	CDD:410758	130/477 (27%)