Protein Alignment spo and Cyp21a1

DIOPT Version :9

• Sequence 1: NP_001286943.1
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_034125.2
• Gene: Cyp21a1 / 13079
• MGIID: 88591
• Length: 487
• Species: Mus musculus
• Alignment Length: 573
• Identity: 138/573 - (24%)
• Similarity: 223/573 - (38%)
• Gaps: 138/573 - (24%)

  Fly     5 LIYTILAILLSVLATSYICIIYGVKRRVLQPVKTKNSTEINHNAYQKYTQAPGPRPWPIIGNLHL 69
            |:..:|.:||.:..|.::...:.:::..|.|:                  ||        |.||.
Mouse     2 LLPGLLLLLLLLAGTRWLWGQWKLRKLHLPPL------------------AP--------GFLHF 40

  Fly    70 LDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSGRPDFIRYHKLF 134
            |.........|.|   |:.|.||.:..|....:|:|:...|.|.|.|.....:|||     |.|
Mouse    41 LQPNLPIYLLGLT---QKLGPIYRIRLGMQDVVVLNSNRTIEEALIQKWVDFAGRP-----HML- 96

  Fly   135 GGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYM-----------KMSQIGCEEMEHWNRE 188
            .|:....|:|.|:|.:.:..:.|:|        |...:           :::|..||.|
Mouse    97 NGKMDLDLSLGDYSLMWKAHKKLSR--------SALMLGMRDSMEPLIEQLTQEFCERM------ 147

  Fly   189 LGNQLVPGEPINIKPLILKACANMFSQYMCSL--RFDYDDVD----------FQQIVQYFDEIFW 241
               :...|.|:        |....||...||:  ...:.|.|          .|.::|.::.  |
Mouse   148 ---RAQAGTPV--------AIHKEFSFLTCSIISCLTFGDKDSTLVQTLHDCVQDLLQAWNH--W 199

  Fly   242 EINQGHPLDFLPWLYPFYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDRDFTDALLKSL 306
            .|   ..|..:|.|.......|.|:.....:....:.:::.||::..|  ....:|..|.:|:.:
Mouse   200 SI---QILTIIPLLRFLPNPGLQKLKQIQESRDHIVKQQLKRHKDSLV--AGQWKDMIDYMLQGV 259

  Fly   307 ---LEDKDVSR----NTIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEEIDAIIEEEN 364
               .:.||..|    :..:.:::.||||.......:...:|::..:.:|.:|:|||:|..:...:
Mouse   260 EKQRDGKDEERLHEGHVHMSVVDLFIGGTETTATTLSWAVAFLLHHPEIQKRLQEELDLKLGPGS 324

  Fly   365 RSINLLDMNAM--PYTMATIFEVLRYSSSPIV----PHVATEDTVISGYGVTKGTIVFINNYVLN 423
            :   ||..|.|  |..||||.||||.  .|:|    ||.||..:.||||.:.|..::..|....|
Mouse   325 Q---LLYRNRMQLPLLMATIAEVLRL--RPVVPLALPHRATRASSISGYDIPKDMVIIPNIQGAN 384

  Fly   424 TSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIGKRTCIGQ 488
            ..|..|..|.:|.|.|||||.|.                          |....|..|.|.|:|:
Mouse   385 LDEMVWELPSKFWPDRFLEPGKN--------------------------PRTPSFGCGARVCLGE 423

  Fly   489 NLVRGFGFLVVVNVMQRYNISSHNPSTI-KISPESLA---LPADCFPLVLTPR 537
            .|.|...|:|:..::|.:.:......|: .:.|:..|   ||...|.:.|.||
Mouse   424 PLARLELFVVLARLLQAFTLLPPPDGTLPSLQPQPYAGINLPIPPFQVRLQPR 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_001286943.1	p450	56..540	CDD:299894	130/522 (25%)
Cyp21a1	NP_034125.2	p450	29..471	CDD:278495	130/539 (24%)
		Steroid-binding. /evidence=ECO:0000250	334..350		9/17 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000