Protein Alignment spo and Cyp1a1

DIOPT Version :10

• Sequence 1: NP_647975.2
• Gene: spo / 38631
• FlyBaseID: FBgn0003486
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_034122.1
• Gene: Cyp1a1 / 13076
• MGIID: 88588
• Length: 524
• Species: Mus musculus
• Alignment Length: 533
• Identity: 150/533 - (28%)
• Similarity: 233/533 - (43%)
• Gaps: 89/533 - (16%)

  Fly    16 VLATSYICIIYGVKR--RVLQPVKTKNSTEINHNAYQKYTQAPGPRPWPIIGNLHLLDRYRDSPF 78
            :||.:..|:.:.|.|  |...|...|.              .|||...|.||::..:.:   :|.
Mouse    17 LLAVTVFCLGFWVVRATRTWVPKGLKT--------------PPGPWGLPFIGHMLTVGK---NPH 64

  Fly    79 AGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSGRPDFIRYHKLFGGERSNSLA 143
            ...|.|:|||||:..:..|.|..:|::.|..|::.|.:.|....||||...:..:..|:   |:.
Mouse    65 LSLTRLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVRQGDDFKGRPDLYSFTLITNGK---SMT 126

  Fly   144 L-CDWSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEMEHWNRELGNQLVP---------GEP 198
            . .|...:...||.||:.  :.:.||......|...|...||.::| .|.||.         |..
Mouse   127 FNPDSGPVWAARRRLAQN--ALKSFSIASDPTSASSCYLEEHVSKE-ANYLVSKLQKVMAEVGHF 188

  Fly   199 INIKPLILKA----CANMFSQYMCSLRFDYDDVDFQQIVQYFDEIFWEI-NQGHPLDFLPWLYPF 258
            ...|.|::..    ||..|.|     |:|:||.:...||...:| |.|: ..|:|.||:|.|...
Mouse   189 DPYKYLVVSVANVICAICFGQ-----RYDHDDQELLSIVNLSNE-FGEVTGSGYPADFIPVLRYL 247

  Fly   259 YQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDRDFTDALLKSLLEDKDVSRN-------- 315
            ....|:...:.:.....| |:::|:....:.:... .||.||:|::. .:|:.:..|
Mouse   248 PNSSLDAFKDLNDKFYSF-MKKLIKEHYRTFEKGH-IRDITDSLIEH-CQDRKLDENANVQLSDD 309

  Fly   316 -TIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEEIDAIIEEENRSINLLDMNAMPYTM 379
             .|..:|:.|..|...|...:...|.|:..|..:.|:||||:|.:|..: |...|.|...:||..
Mouse   310 KVITIVLDLFGAGFDTVTTAISWSLMYLVTNPRVQRKIQEELDTVIGRD-RQPRLSDRPQLPYLE 373

  Fly   380 ATIFEVLRYSS-SPI-VPHVATEDTVISGYGVTKGTIVFINNYVLNTSEKFWVNPKEFNPLRFLE 442
            |.|.|..|:|| .|. :||..|.||.::|:.:.||..||:|.:.:|...:.|.:|.||.|.|||.
Mouse   374 AFILETFRHSSFVPFTIPHSTTRDTSLNGFYIPKGCCVFVNQWQVNHDRELWGDPNEFRPERFLT 438

  Fly   443 PSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIGKRTCIGQNLVRGFGFLVVVNVMQRYN 507
            ||.....:.|           ||:.|         |.:|||.|||:.:.|...||.:..::|:..
Mouse   439 PSGTLDKRLS-----------EKVTL---------FGLGKRKCIGETIGRSEVFLFLAILLQQIE 483

  Fly   508 ISSHNPSTIKISP 520
                    .|:||
Mouse   484 --------FKVSP 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_647975.2	CYP1_2-like	89..520	CDD:410710	128/456 (28%)
Cyp1a1	NP_034122.1	Mitochondrial targeting signal. /evidence=ECO:0000250|UniProtKB:P00185	33..44		3/24 (13%)
		CYP1A	74..509	CDD:410769	131/459 (29%)