DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spo and LOC100148115

DIOPT Version :9

Sequence 1:	NP_001286943.1	Gene:	spo / 38631	FlyBaseID:	FBgn0003486	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_001315620.1	Gene:	LOC100148115 / 100148115	-ID:	-	Length:	496	Species:	Danio rerio

Alignment Length:	535	Identity:	146/535 - (27%)
Similarity:	227/535 - (42%)	Gaps:	107/535 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLAALIYTILAILLSVLATSYICIIYGVKRRVLQPVKTKNSTEINHNAYQKYTQAPGPRPWPIIG 65
            ||.||:...|...|..|           :.|:.:|   ||.             .|||.|.||.|
Zfish     1 MLTALVLLCLGAFLLYL-----------QLRIRRP---KNF-------------PPGPAPVPIFG 38

  Fly    66 NLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSGRPDFIRY 130
            ||..|:|.  ||...|...||.||.||.:..|....:|:...::|:|.|.......|||.:.:.:
Zfish    39 NLLQLNRI--SPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMF 101

  Fly   131 HKLFGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEMEHWNRELGNQLVP 195
            ..:.||:   .:.:.|:.:..::.|..|.  .:.|.|......|.|...||::|....|...  .
Zfish   102 SHVTGGK---GVIMADYGESWREHRRFAL--TTLRNFGLGKKSMEQRILEEVKHICLLLEES--A 159

  Fly   196 GEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQYFDEIFWEINQGHPLDFLPW--LY-- 256
            |:.|:.:.|..:|.:|:.:..:...||:|.|..||.::...::: .:|..|      ||  ||
Zfish   160 GKSIDPQHLYHQAASNIIASIIFGSRFNYKDAYFQTLITSVEDL-TKITIG------PWAMLYEI 217

  Fly   257 ---------PFYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDRDFTDALLKSLLEDKDV 312
                     ||     .|...:...|...:::.:..|:...| ..|| ||..|..|:. :|:|..
Zfish   218 APVLRIFPLPF-----QKAFQYFEQITKHVLKVVEEHKTSRV-AGEP-RDLIDCYLEE-MENKSD 274

  Fly   313 SRN--------TIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEEIDAIIEEENRSINL 369
            .|.        |::|.|  ||.|.....|.:..:..|:.....|..:.|.|||.::...:. :..
Zfish   275 HRTSFDESQMVTLLFDL--FIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDH-VTY 336

  Fly   370 LDMNAMPYTMATIFEVLRYSSSPIVP----HVATEDTVISGYGVTKGTIV--FINNYVLNTSEKF 428
            .|.|||.:..|.|.|..|.:.  |.|    |.|..||.:.||.:.||||:  ::::.:...|:
Zfish   337 EDRNAMHFVQAVIHEGQRVAD--IAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREESQ-- 397

  Fly   429 WVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIGKRTCIGQNLVRG 493
            |..|.||||..||                     |||.:..:| ..|:|||.|.|.|:|:||.|.
Zfish   398 WKFPHEFNPQNFL---------------------NEKGEFVKN-DAFMPFSAGPRVCLGENLARM 440

  Fly   494 FGFLVVVNVMQRYNI 508
            ..||::|.|::|:.:
Zfish   441 ELFLILVTVLRRFRL 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spo	NP_001286943.1	p450	56..540	CDD:299894	135/480 (28%)
LOC100148115	NP_001315620.1	p450	28..483	CDD:278495	135/481 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45226
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920