DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)psg2 and Son

DIOPT Version :9

Sequence 1:	NP_647974.1	Gene:	l(3)psg2 / 38630	FlyBaseID:	FBgn0035617	Length:	1929	Species:	Drosophila melanogaster
Sequence 2:	NP_001262426.1	Gene:	Son / 41159	FlyBaseID:	FBgn0037716	Length:	874	Species:	Drosophila melanogaster

Alignment Length:	1078	Identity:	209/1078 - (19%)
Similarity:	341/1078 - (31%)	Gaps:	341/1078 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GSAVGMEQPATGKQLKPPEDLQDNDTNSLEPGEVVTPPHYHPSSPAVKKHLSKELMISKTLR--- 68
            |::|...|.| |.|..||..         ||..:...|      |...|....:..:...||
  Fly     8 GASVETPQVA-GSQTNPPVQ---------EPLALTKIP------PIKVKSERPDAEVEAKLRAMN 56

  Fly    69 -KLPVSVVEQARKENGSGGTPNAQAEDADDSEGLYSESDSSGEDLKNVEDVQKARKEKQEEAAAA 132
             |:...:|...|:.|.:        |..::.|...|||.:|.:|.||::.|:
  Fly    57 AKIKAEMVTLMRRSNSN--------ELGNNDESGESESSASADDKKNIKPVK------------- 100

  Fly   133 TLPQAPPTPFLGINPLRFHMRAPCFEFPRMGFMPRMNRGGPRGMRPTFFGRPPAANRMGAPMMGG 197
                                                                 ::|.:.|.:.|
  Fly   101 -----------------------------------------------------SSNEILAELFG- 111

  Fly   198 LPTQGPPPGAYAPQNPPPTGINSNSGRCKRLQSDVIWTALQPPVSFVFNLVSECSNTKHENCRTK 262
                                               ::.|..|......||..:....|.|....|
  Fly   112 -----------------------------------VFNAAPPEELLDDNLFKKKKKVKKEKKDKK 141

  Fly   263 AETTDHNSKESKLPSETKSTEPLIENNRSRELPQHKNYVRGKTSNRSHDRTQNRGRTRERSKESH 327
            |:    ..|.:|...|...:|...::...|:..:||: :|.|...:..||.:::.:.|:|
  Fly   142 AK----KKKTTKSDGECSDSEAEGKHKHKRKKHKHKD-IRVKDKEKDRDRDKSKEKDRDR----- 196

  Fly   328 GKSTENSKNKDEGRGKGRERDLFRRKSRERSQDKNLNRAKSMNLSKEKDEVGGEPRNTASGKSQE 392
              .|:.||.||      |:||    :.|::|:||...........|||.|.........|..|::
  Fly   197 --VTDKSKEKD------RDRD----RDRDKSKDKFTAAQAPSEKEKEKSESRKRSAVEPSSHSEK 249

  Fly   393 RDQSRGKTKDRSRERDRTRNKTREKSQARDQTRSKAN----DAEHTRAKSRKRSSSRDKR-REKS 452
            |::     .:|.:.||..|.:.|||...|::.||..:    ..|..|.|..:.:|::.:: ::.|
  Fly   250 RER-----HEREKHRDWEREREREKEHERERVRSNNSFYNGQREADRLKGSESASTKSRQEQDLS 309

  Fly   453 KEKLGDKEK--NEDLSKEKLEGKSTEHSEKRNESKVKNKDTNEENA--NKKLRERSKDRNHSKER 513
            ...|.|:|.  .|..|..:....::.:.||...|....::..|.|.  |:|.|.||:|....|:|
  Fly   310 DISLSDEESYLREKASNGRRRAHNSFYDEKEELSVSPKRNVRESNTRRNRKSRSRSRDLGIDKKR 374

  Fly   514 LHERTQ----------------NKSEERKPE------------------AKKVRNA-----IENS 539
            |.|..:                |.:.|.|.:                  .||:.|.     :.:.
  Fly   375 LLEIARRNAINMFKQGTMPGVANMTAEVKDKVLVKMRYGGRTIQDLTDFCKKISNGDGLSDLSSE 439

  Fly   540 KEAPTDR-----------------------KKDKLLGPLGEKTDERSK---------DKQIKRSR 572
            :|:..|:                       :....|.|...:.||::|         ..|..|:.
  Fly   440 EESDVDKNGNAKVFHHPFQLKEREPIVMHIRNSTALVPAPPRLDEQTKAITMQFPVSSGQTHRNN 504

  Fly   573 EQSVTKCPKESGKDTLMEHPPQENGLDGSKRSSMPHESFSESAKTREHASRRKNQTLSPWGSREG 637
            |..|...||:| ...|...||.:...:..|.:  |...|::|...:|    ::.....|.|....
  Fly   505 EVWVPVDPKDS-LVPLPSLPPAKQATNMFKET--PKNVFAKSIPLQE----QQEPAFKPLGGAVV 562

  Fly   638 TPPMTPPQVQIPQTPIVDIANPKDFDIFADSPPRVNTAVSAPAATIERSTTPPLKSSIPIVPIAK 702
            .||:.  ..|:|..|             ...||           |:.:...||....:|.|||..
  Fly   563 VPPLA--ATQLPTVP-------------QSVPP-----------TVPKEFAPPAVPFVPEVPIPS 601

  Fly   703 ADKLAPLLKASEIHSRIGALLEESDLHLDNLLATKEQLFRRTNEYKERKEAPKEIKAEYLPNSRH 767
            ...:.|:..||     |...:....:.:.:::..:....||..|.....||   :|..|  .::.
  Fly   602 TSPVTPMQSAS-----IFPDVTPPSMDVSSIITQRLSAIRRLQENPADSEA---LKMMY--TAQR 656

  Fly   768 NRSATGRAEVEHHKSQPRHINPFKRESVLSGRKSSSRPSSKERRFQRHDSEVENWDRDLELERNQ 832
            |.|:...:     |..|..........|:...:.:|.|....|:.|...::.......:.|.:..
  Fly   657 NMSSWANS-----KHLPGQFTGSTGAQVMKAHELNSGPQLWVRKDQMTSTKPVTGGMGMALLQKM 716

  Fly   833 -------LNGSQLTGFQPRKSD-EYTKFSIKKEKDLTPPPLQTNFTRTTIKIERN---------- 879
                   |...:....||...| :..|..:....||.||.:     |......||
  Fly   717 GWKPGEGLGRCKTGSLQPLLLDVKLDKRGLVSRDDLRPPQM-----RAPAAQRRNKNMAGPIGAG 776

  Fly   880 --------------ATP-PRHMEHDVLVRNGAVATN--APPPAKEQESPDTDDYIDNWENDDSLA 927
                          :|| ....:|.|.|.|...:.|  .||..|.::.      |....|...|.
  Fly   777 PCPAVQGAGPGPLASTPLVTQDKHPVCVLNELTSKNKWMPPQYKLRQD------IGPAHNRSFLF 835

  Fly   928 SMPKNAPPVTPTPAPN--ANASLNATP--------LPP 955
            |:..|....||....|  ..|.|||..        |||
  Fly   836 SVEINGQTFTPDRGSNNKKEAKLNAAALCLRSLGILPP 873

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)psg2	NP_647974.1	PRP38_assoc	374..450	CDD:289628	20/80 (25%)
Son	NP_001262426.1	PHA03247	<455..627	CDD:223021	40/209 (19%)
		G-patch	705..747	CDD:396249	6/41 (15%)
		DSRM_SON-like	798..872	CDD:380699	20/79 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2BZCQ
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900