Protein Alignment l(3)psg2 and Srek1

DIOPT Version :10

• Sequence 1: NP_647974.1
• Gene: l(3)psg2 / 38630
• FlyBaseID: FBgn0035617
• Length: 1929
• Species: Drosophila melanogaster
• Sequence 2: XP_036013913.1
• Gene: Srek1 / 218543
• MGIID: 2145245
• Length: 631
• Species: Mus musculus
• Alignment Length: 673
• Identity: 164/673 - (24%)
• Similarity: 263/673 - (39%)
• Gaps: 198/673 - (29%)

  Fly     8 SAVGMEQPAT-----GK----QLKPPEDLQDNDTNSLEPGEVVTPPHYHPSSPAVKKHLSKELMI 63
            |||..||..|     |:    :|.||:     :|......:|.......|||..|.:||:..:.|
Mouse    28 SAVTSEQMRTLFSFLGEIEELRLYPPD-----NTPLAFSSKVCYIKFRDPSSVGVAQHLTNTVFI 87

  Fly    64 SKTLRKLPVS---VVEQARKEN-------------GSGGTPNAQAEDADDSEGLYSESDSSGEDL 112
            .:.|..:|.:   :.|:|:..:             |:|..|      ...|..|.:.| |.|..|
Mouse    88 DRALIVVPCAEGKIPEEAKALSLLAPAPTMTSLVPGAGLLP------IPTSSPLTAVS-SLGVSL 145

  Fly   113 KNVEDVQKARKEKQEEAAAATLPQAPPTPFLG-INPLRF-HMRAPCFE----------------F 159
            .::..:..|..:..    ..||.:.|..|.:| ::|.:. .:|...:.                |
Mouse   146 SSLGAIPAAALDPN----ITTLGEIPQPPLMGNVDPSKIDEIRRTVYVGNLNSQTTTADQLLEFF 206

  Fly   160 PRMGFMPRMNRGGPRGMRPTFFGRPPAANRMGAP--------MMGGLPTQ---------GPP--- 204
            .::|.:..:...|.. .:||.|.....|::...|        |.|..|.:         .||
Mouse   207 KQVGEVKFVRMAGDE-TQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMT 270

  Fly   205 PGAYAPQNPPPTGINSNSGRCKRLQSDVIWTALQPPVSFVFNLVSECSNTKHENCRTKAETTDHN 269
            |.|.|.:      :.....|.:..|| .|..|::|.        |..|| :.:..|:::.|
Mouse   271 PQAAAKE------LEEVMKRVREAQS-FISAAIEPE--------SGKSN-ERKGGRSRSHT---- 315

  Fly   270 SKESKLPSETKSTEPLIENNRSRELPQHKNYVRGKTSNRSHDRTQNRGRTRERSKESHGKSTENS 334
              .||..|.:||     .:.|.|...:|:        :|||:|:::|.:.|.|||..|.|
Mouse   316 --RSKSRSSSKS-----HSRRKRSQSKHR--------SRSHNRSRSRQKDRRRSKSPHKK----- 360

  Fly   335 KNKDEGRGKGRERDLFRRKSRERSQDKNLNRAKSMNLSKEKDEVGGEPRNTASGKSQERDQSRGK 399
                  |.|.||    |||||.||:.::          |.||                   :|.|
Mouse   361 ------RSKSRE----RRKSRSRSRSRD----------KRKD-------------------TREK 386

  Fly   400 TKDRSRERDRTRNKTREKSQARDQTRSKANDAEHTRAKSRKRSSSRDKRREKSKEKLGDKEKNED 464
            .|:|.:|::|.:.:.|||.:.:|:.|.|..|.:  |.|.:.....|||.:||.::|  |||:.:|
Mouse   387 VKERVKEKEREKEREREKDREKDKERGKNKDKD--REKEKDHEKERDKEKEKEQDK--DKEREKD 447

  Fly   465 LSKEKLEGKSTEHSEKRNESKVKNKDTNEENANKKLRERSKDRNHSKERLHERTQNKSEERKPEA 529
            .|||.        .|||.:.|.........||:::.|..|::|        .|.:::|..|.|..
Mouse   448 RSKET--------DEKRKKEKKSRTPPRSYNASRRSRSTSRER--------RRRRSRSSSRSPRT 496

  Fly   530 KKVRNAIENSKEAPTDRKKDKLLGPLGEKTDERSKDK-QIKRSREQSVTKCPKESGKDTLMEHPP 593
            .|  .....|..:|:.|.::|     .||..|:.:|. ..:|.||:| |...|.||
Mouse   497 SK--TVKRKSSRSPSPRGRNK-----KEKKREKERDHISDRRERERS-TSTKKSSG--------- 544

  Fly   594 QENGLDGSKRSSMPHESFSESAK 616
            ..:|.:..::|:.| ...|.||:
Mouse   545 DRDGKEKVEKSTTP-VKVSRSAR 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)psg2	NP_647974.1	PTZ00121	<308..>573	CDD:173412	76/265 (29%)
Srek1	XP_036013913.1	RRM1_SREK1	20..99	CDD:409941	21/75 (28%)
		RRM2_SREK1	181..266	CDD:409705	12/85 (14%)