Protein Alignment Lkr and Grpr

DIOPT Version :10

• Sequence 1: NP_647968.3
• Gene: Lkr / 38622
• FlyBaseID: FBgn0035610
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_036838.2
• Gene: Grpr / 24938
• RGDID: 2750
• Length: 384
• Species: Rattus norvegicus
• Alignment Length: 371
• Identity: 104/371 - (28%)
• Similarity: 177/371 - (47%)
• Gaps: 64/371 - (17%)

  Fly    14 FLPGAEEEAEFERLYAAPAEIVALLSIFYGGISIVAVIGNTLVIWVVATTRQMRTVTNMYIANLA 78
            |.||.        :|..||        .||.|.::.:|||..:|.:..|.:.||.|.|::|::||
  Rat    36 FHPGI--------IYVIPA--------VYGLIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLA 84

  Fly    79 FADVIIGLFCIPFQFQAALLQSWNLPWFMCSFCPFVQALSVNVSVFTLTAIAIDRHRAIINPLRA 143
            ..|:::.:.|.|......|...|......|...||:|..||.||||||||::.||::||:.|:..
  Rat    85 LGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDI 149

  Fly   144 RPTKFVSKFIIGG--IWMLALLFAVPFAI-----AFRVEELTERFRENNETYNVTRPFCMNKNLS 201
            :.:..:.|..:..  ||::::|.|:|.|:     .|.|       ::.|:|:....|: .:.|..
  Rat   150 QASHALMKICLKAALIWIVSMLLAIPEAVFSDLHPFHV-------KDTNQTFISCAPY-PHSNEL 206

  Fly   202 DDQLQSFRYTLVFVQYLVPFCVISFVYIQMAVRL----WGTRAPGNAQDSRDITLLKNKKKVIKM 262
            ..::.|....|||  |::|..:||..|..:|..|    :.....||....:.|   :::|::.|.
  Rat   207 HPKIHSMASFLVF--YIIPLSIISVYYYFIARNLIQSAYNLPVEGNIHVKKQI---ESRKRLAKT 266

  Fly   263 LIIVVIIFGLCWLP---LQLYNILYVTIPEINDYHFISIVWFCCDWLAMSNSCYNPFIYGIYNEK 324
            :::.|.:|..||||   :.||...:.:..:.:..|||:.:  |...||.:|||.|||...:.::.
  Rat   267 VLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFITSI--CARLLAFTNSCVNPFALYLLSKS 329

  Fly   325 FKREFNK-----------------RFAACFCKFKTSMDAHERTFSM 353
            |:::||.                 |...|...||::..:  .|||:
  Rat   330 FRKQFNTQLLCCQPSLLNRSHSTGRSTTCMTSFKSTNPS--ATFSL 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lkr	NP_647968.3	7tmA_leucokinin-like	36..329	CDD:320515	89/306 (29%)
		TM helix 1	37..63	CDD:320515	7/25 (28%)
		TM helix 2	70..95	CDD:320515	7/24 (29%)
		TM helix 3	108..138	CDD:320515	17/29 (59%)
		TM helix 4	149..170	CDD:320515	6/22 (27%)
		TM helix 5	205..234	CDD:320515	10/28 (36%)
		TM helix 6	254..284	CDD:320515	10/32 (31%)
		TM helix 7	297..322	CDD:320515	9/24 (38%)
Grpr	NP_036838.2	7tmA_GRPR	42..334	CDD:320252	92/314 (29%)
		TM helix 1	43..69	CDD:320252	9/33 (27%)
		TM helix 2	76..102	CDD:320252	7/25 (28%)
		TM helix 3	114..144	CDD:320252	17/29 (59%)
		TM helix 4	156..176	CDD:320252	5/19 (26%)
		TM helix 5	208..233	CDD:320252	9/26 (35%)
		TM helix 6	258..288	CDD:320252	9/29 (31%)
		TM helix 7	302..327	CDD:320252	11/26 (42%)