DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lkr and Gpr83

DIOPT Version :9

Sequence 1:	NP_647968.3	Gene:	Lkr / 38622	FlyBaseID:	FBgn0035610	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_536336.1	Gene:	Gpr83 / 140595	RGDID:	619891	Length:	422	Species:	Rattus norvegicus

Alignment Length:	320	Identity:	107/320 - (33%)
Similarity:	169/320 - (52%)	Gaps:	24/320 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RLYAAPAE---IVALLSIFYGGISIVAVIGNTLVIWVVATTRQMRTVTNMYIANLAFADVIIGLF 87
            |.|.|.::   :.|||.:.|..|.:.::.||.||..|:...::|.:.|:::|.|||.||::|.|.
  Rat    58 RRYGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLL 122

  Fly    88 CIPFQFQAALLQSWNLPWFMCSFCPFVQALSVNVSVFTLTAIAIDRHRAIINPLRARPTKFVSKF 152
            ..||.....:..:|.....||....|.|..|::||..||||||:|||:.|::||:.|.:......
  Rat   123 NTPFTLVRFVNSTWVFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPRISITKGVI 187

  Fly   153 IIGGIWMLALLFAVPFAIAFRVEELTERFRENNETYNVTRPFCMNKNLSD-----DQLQSFRYTL 212
            .|..||::|..|::|.||..::  .|.::.|     ::.|..|    |.|     |....:....
  Rat   188 YIAVIWVMATFFSLPHAICQKL--FTFKYSE-----DIVRSLC----LPDFPEPADLFWKYLDLA 241

  Fly   213 VFV-QYLVPFCVISFVYIQMAVRLWGTRAPGNAQDSRDITLLKNKKKVIKMLIIVVIIFGLCWLP 276
            .|: .||:|..:||..|.::|.:||.....|:....:.:.|.:.||..:|||::||::|.|||.|
  Rat   242 TFILLYLLPLFIISVAYARVAKKLWLCNTIGDVTTEQYLALRRKKKTTVKMLVLVVVLFALCWFP 306

  Fly   277 LQLYNILYVTIPEINDYHFISIVWFCCDWLAMSNSCYNPFIYGIYNEKFKREFNKRFAAC 336
            |..| :|.::...|   |..:.::|...|.|||::|||||||...||.|:.|.....:.|
  Rat   307 LNCY-VLLLSSKAI---HTNNALYFAFHWFAMSSTCYNPFIYCWLNENFRVELKALLSMC 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lkr	NP_647968.3	7tm_4	46..329	CDD:304433	97/288 (34%)
		7tm_1	52..318	CDD:278431	92/271 (34%)
		PHA03216	467..>519	CDD:177558
Gpr83	NP_536336.1	7tm_4	77..>224	CDD:304433	52/157 (33%)
Gpr83	NP_536336.1	7tm_1	87..344	CDD:278431	92/271 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1254727at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X257
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920