Protein Alignment Lkr and brs3

DIOPT Version :10

• Sequence 1: NP_647968.3
• Gene: Lkr / 38622
• FlyBaseID: FBgn0035610
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: XP_002932668.2
• Gene: brs3 / 100488712
• XenbaseID: XB-GENE-960289
• Length: 402
• Species: Xenopus tropicalis
• Alignment Length: 335
• Identity: 101/335 - (30%)
• Similarity: 176/335 - (52%)
• Gaps: 15/335 - (4%)

  Fly    10 SRLEFLPGAEEEAEFERLYAAP-AEIVALLSIFYGGISIVAVIGNTLVIWVVATTRQMRTVTNMY 73
            :.|.|..|::...:.|....:| .|::|.:||.|..|..|.::|||::|.|....:.|:||.|::
 Frog    20 AHLRFSNGSDALYQEESADLSPRLEVLATISITYAVIISVGLLGNTILIKVFFKVKSMQTVPNIF 84

  Fly    74 IANLAFADVIIGLFCIPFQFQAALLQSWNLPWFMCSFCPFVQALSVNVSVFTLTAIAIDRHRAII 138
            |.:|||.|:::.|.|:|......::.:|......|....|:|..||.|||||||.::.||:|||:
 Frog    85 ITSLAFGDLLLLLTCVPVDASRYMVDTWLFGRMGCKILSFIQLTSVGVSVFTLTVLSADRYRAIV 149

  Fly   139 NPLRARPTKFVSKFI--IGGIWMLALLFAVPFAIAFRVEELTERFRENNETYNVTRPFCMNKNLS 201
            .||..:.:..|.|..  ...:|::::|.|.|.|:...:.|.:.  .:.|.::....|:.:::.|.
 Frog   150 KPLELQTSDAVLKTCGKAACVWIISMLLAAPEAVFSDLYEFSS--PDKNTSFKACAPYPVSEKLM 212

  Fly   202 DDQLQSFRYTLVFVQYLVPFCVISFVYIQMAVRLWGTRAPGNAQD-SRDITLLKNKKKVIKMLII 265
             .:..|....|||  |:||..:||..||.:|..|:.:.....|:: :.....::::|:|.|.:::
 Frog   213 -QETHSLMCFLVF--YIVPLSIISAYYILIAKTLYKSTFNMPAEEHTHARKQIESRKRVAKTVLV 274

  Fly   266 VVIIFGLCWLP---LQLY-NILYVTIPEINDYHFISIVWFCCDWLAMSNSCYNPFIYGIYNEKFK 326
            :|.:|..||||   |.|| :..|.:....:..|..:.::  ...||.||||.|||.....:..|:
 Frog   275 LVALFAFCWLPNHILYLYRSFTYHSAVNSSMLHLSATIF--ARILAFSNSCVNPFALYWLSRSFR 337

  Fly   327 REFNKRFAAC 336
            :.|.|:...|
 Frog   338 QHFKKQVYCC 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lkr	NP_647968.3	7tmA_leucokinin-like	36..329	CDD:320515	92/299 (31%)
		TM helix 1	37..63	CDD:320515	10/25 (40%)
		TM helix 2	70..95	CDD:320515	9/24 (38%)
		TM helix 3	108..138	CDD:320515	16/29 (55%)
		TM helix 4	149..170	CDD:320515	6/22 (27%)
		TM helix 5	205..234	CDD:320515	12/28 (43%)
		TM helix 6	254..284	CDD:320515	12/33 (36%)
		TM helix 7	297..322	CDD:320515	9/24 (38%)
brs3	XP_002932668.2	7tm_GPCRs	47..340	CDD:475119	92/299 (31%)
		TM helix 1	49..73	CDD:410628	10/23 (43%)
		TM helix 2	82..104	CDD:410628	9/21 (43%)
		TM helix 3	120..142	CDD:410628	11/21 (52%)
		TM helix 4	165..181	CDD:410628	3/15 (20%)
		TM helix 5	214..237	CDD:410628	9/24 (38%)
		TM helix 6	269..291	CDD:410628	8/21 (38%)
		TM helix 7	308..333	CDD:410628	9/26 (35%)